PET-CT in early detection of Alzheimer’s disease: а case report

Semen V. Prokopenko; Прокопенко Семен В.; Boris V. Barankin; Баранкин Борис В.; Natal'ya М. Mar'ina; Марьина Наталья М.; Еlena Y. Mozheyko; Можейко Елена Ю.; Аnna F. Bezdenezhnykh; Безденежных Анна Ф.; Tat'yana D. Koryagina; Корягина Татьяна Д.; Natal'ya G. Chanchikova; Чанчикова Наталья Г.; Nikolay А. Tokarev; Токарев Николай А.; Еlena А. Karlova; Карлова Елена А.; Аnastasiya V. Ozerskaya; Озерская Анастасия В.; Еvgeniy А. Badrin; Бадрин Евгений А.; Кirill V. Belugin; Белугин Кирилл В.; Аnastasiya А. Savel'eva; Савельева Анастасия А.; Nikolay V. Shepelevich; Шепелевич Николай В.

doi:10.18454/ACEN.2017.4.7

PET-CT in early detection of Alzheimer’s disease: а case report

Authors: Prokopenko S.V.¹, Barankin B.V.², Mar'ina N.М.², Mozheyko Е.Y.¹, Bezdenezhnykh А.F.¹, Koryagina T.D.¹, Chanchikova N.G.², Tokarev N.А.², Karlova Е.А.², Ozerskaya А.V.², Badrin Е.А.², Belugin К.V.², Savel'eva А.А.², Shepelevich N.V.²
Affiliations:
1. Krasnoyarsk State Medical University named after Prof. V.F. Voyno-Yasenetsky
2. Federal Siberian Research Clinical Center
Issue: Vol 11, No 4 (2017)
Pages: 65-70
Section: Clinical analysis
URL: https://annaly-nevrologii.com/journal/pathID/article/view/501
DOI: https://doi.org/10.18454/ACEN.2017.4.7
ID: 501

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Abstract

The article describes a clinical case of a female Alzheimer disease patient at an early stage of the neurodegenerative process. The patient did not have any complaints. She was taken to the neuropsychologist’s by her husband that was concerned because of the patient's family history (his mother-in-law suffered of Alzheimer's disease) and the emergence of some memory problems in his wife. The diagnosis was suspected based on the results of neuropsychological evaluation of cognitive functions which corresponded to mild cognitive impairment. To confirm the presence of a neurodegenerative disease brain positron-emission tomography with F-18 fluorodesoxyglucose (FDG) was performed. Hypometabolism of the imaging agent was detected in the temporal and parietal lobes cortex, in the association cortex of the left temporal and the right occipital lobes, and in the posterior part of the left cyngulate gyrus. This findings correlated with the data of the patient’s cognitive evaluation and thus provided the nosological diagnosis at an early stage of the disease.

Keywords

Alzheimer's disease, early detection, positron-emission tomography

References

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PET-CT in early detection of Alzheimer’s disease: а case report

Full Text

Abstract

Keywords

About the authors

References

Supplementary files

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