Current neurosurgical approaches to treatment of structural epilepsies

Cover Page


Cite item

Full Text

Abstract

The drug-resistant epilepsy remains one of the major problems in contemporary neurology. However, the new surgical approaches showed their great efficacy in treatment of patients with intractable seizures. The relevant neurosurgical methods of epilepsy treatment, as well as the issues of preoperative diagnostics and indications for operative treatment are described in this review. We also present a clinical case which demonstrates the successful treatment of patient with drug-resistant epilepsy who underwent stereotaxic implantation of electrodes in the anterior thalamic nuclei followed by significant clinical improvement.

About the authors

Andrey R. Sitnikov

Federal Center of Treatment and Rehabilitation

Author for correspondence.
Email: neuro77@gmail.com
Russian Federation, Moscow

Victoria A. Skorobogatova

Smolensk State Medical University

Email: neuro77@gmail.com
Russian Federation, Smolensk

Natalia N. Maslova

Smolensk State Medical University

Email: neuro77@gmail.com
Russian Federation, Smolensk

References

  1. Engel J.Jr. What can we do for people with drug-resistant epilepsy. The 2016 Wartenberg Lecture. Neurology 2016; 87: 2483–2489. doi: 10.1212/WNL.0000000000003407. PMID: 27920283.
  2. Engel J.Jr., Wiebe S., French J. et al. Practice parameter: temporal lobe and localized neocortical resections for epilepsy: report of the Quality Standards Subcommittee of the American Academy of Neurology, in association with the American Epilepsy Society and the American Association of Neurology. Neurology 2003; 60: 538–547. PMID: 12601090.
  3. Engel J.Jr, McDermott M.P., Wiebe S. et al. Early surgical therapy for drug-resistant temporal lobe epilepsy. JAMA 2012; 307: 922–930. doi: 10.1001/jama.2012.220. PMID: 22396514.
  4. Berg A.T., Langfitt J., Shinnar S. et al. How long does it take for partial epilepsy to become intractable? Neurology 2003; 60: 186–190. PMID: 12552028.
  5. Picot M.C., Jaussent A., Neveu D. et al. Cost-effectiveness analysis of epilepsy surgery in a controlled cohort of adult patients with intractable partial epilepsy : a 5-year follow-up study. Epilepsia 2016; 57: 1669–1679. doi: 10.1111/epi.13492. PMID: 27595433.
  6. Englot D.J., Ouyang D., Garcia P.A. et al. Epilepsy surgery trends in the United States, 1990–2008. Neurology 2012 ;78 :1200–1206. doi: 10.1212/WNL.0b013e318250d7ea. PMID: 22442428.
  7. Choi H., Carlino R., Heiman G. et al. Evaluation of duration of epilepsy prior to temporal lobe epilepsy surgery during the past two decades. Epilepsy Res 2009; 86: 224–227. doi: 10.1016/j.eplepsyres.2009.05.014. PMID: 19581072.
  8. Haneef Z., Stern J., Dewar S., Engel J.Jr. Referral pattern for epilepsy surgery after evidence-based recommendations: a retrospective study. Neurology 2010 ;75: 699–704. doi: 10.1212/WNL.0b013e3181eee457. PMID: 20733145.
  9. Bell G.S., de Tisi J., Gonzalez-Fraile J.C. et al. Factors affecting seizure outcome after epilepsy surgery: an observational series. J Neurol Neurosurg Psychiatry 2017;88 : 933–940. doi: 10.1136/jnnp-2017-316211. PMID: 28870986.
  10. Woermann F.G., Barker G.J., Birnie K.D. et al. Regional changes in hippocampal T2 relaxation and volume: a quantitative magnetic resonance imaging study of hippocampal sclerosis. J Neurol Neurosurg Psychiatry 1998; 65: 656–664. PMID : 9810933.
  11. Friedman E. Epilepsy imaging in adults: getting it right. AJR Am J Roentgenol 2014; 203: 1093–1103. doi: 10.2214/AJR.13.12035. PMID: 25341150.
  12. Bauer P.R., Reitsma J.B., Houweling B.M. et al. Can fMRI safely replace the Wada test for preoperative assessment of language lateralisation? A meta-analysis and systematic review. J Neurol Neurosurg Psychiatry 2014; 85: 581–588. doi: 10.1136/jnnp-2013-305659. PMID: 23986313.
  13. Paldino M.J., Yang E., Jones J.Y. et al. Comparison of the diagnostic accuracy of PET/MRI to PET/CT-acquired FDG brain exams for seizure focus detection: a prospective study. Pediatr Radiol 2017; 47: 1500–1507. doi: 10.1007/s00247-017-3888-8. PMID: 28512714.
  14. Duncan J.S., Hamani C. Stimulating the brain for epilepsy. Neurology 2015; 84: 768–769. doi: 10.1212/WNL.0000000000001297. PMID: 25616484.
  15. Helmstaedter C., Richter S., Röske S. et al. Differential effects of temporal pole resection with amygdalohippocampectomy versus selective amygdalohippocampectomy on material-specific memory in patients with mesial temporal lobe epilepsy. Epilepsia 2008; 49:88–97. doi: 10.1111/j.1528-1167.2007.01386.x. PMID: 17941848.
  16. Englot D.J., Wang D.D., Rolston J.D. et al. Rates and predictors of long-term seizure freedom after frontal lobe epilepsy surgery: a systematic review and meta-analysis. J Neurosurg 2012; 116: 1042–1048. doi: 10.3171/2012.1.JNS111620. PMID: 22304450.
  17. Laoprasert P., Ojemann J.G., Handler M.H. Insular epilepsy surgery. Epilepsia 2017 ; 58(suppl 1): 35–45. doi: 10.1111/epi.13682. PMID: 28386920.
  18. Asadollahi M., Sperling M.R., Rabiei A.H., Asadi-Pooya A.A. Drug-resistant parietal lobe epilepsy: clinical manifestations and surgery outcome. Epileptic Disord 2017; 19: 35–39. doi: 10.1684/epd.2017.0893. PMID: 28256447.
  19. Salanova V., Andermann F., Olivier A. et al. Occipital lobe epilepsy: electroclinical manifestations, electrocorticography, cortical stimulation and outcome in 42 patients treated between 1930 and 1991. Surgery of occipital lobe epilepsy. Brain 1992; 115(Pt 6): 1655–1680. PMID : 1486456.
  20. Harward S.C., Chen W.C., Rolston J.D. et al. Seizure outcomes in occipital lobe and posterior quadrant epilepsy surgery: a systematic review and meta-analysis. Neurosurgery 2018; 82: 350–358. doi: 10.1093/neuros/nyx158. PMID: 28419330.
  21. Graham D., Tisdall M.M., Gill D. Corpus callosotomy outcomes in pediatric patients: a systematic review Epilepsia 2016; 57: 1053–1068. doi: 10.1111/epi.13408. PMID: 27237542.
  22. Paglioli E., Martins W.A., Azambuja N. et al. Selective posterior callosotomy for drop attacks: a new approach sparing prefrontal connectivity. Neurology 2016 ;87: 1968–1974. doi: 10.1212/WNL.0000000000003307. PMID: 27733569.
  23. Feng E.S., Sui C.B., Wang T.X., Sun G.L. Stereotactic radiosurgery for the treatment of mesial temporal lobe epilepsy. Acta Neurol Scand 2016; 134: 442–451. doi: 10.1111/ane.12562. PMID: 26846702.
  24. Usami K., Kawai K., Koga T. et al. Delayed complication after Gamma Knife surgery for mesial temporal lobe epilepsy. J Neurosurg 2012; 116: 1221–1225. doi: 10.3171/2012.2.JNS111296. PMID: 22443500.
  25. Wu C., Boorman D.W., Gorniak R.J. et al. The effects of anatomic variations on stereotactic laser amygdalohippocampectomy and a proposed protocol for trajectory planning. Neurosurgery 2015; 11(suppl 2): 345–347. doi: 10.1227/NEU.0000000000000767. PMID: 25850599.
  26. Vakharia V.N., Sparks R., Kuo L. et al. Automated trajectory planning for laser interstitial thermal therapy in mesial temporal lobe epilepsy. Epilepsia 2018; 59: 814–824. doi: 10.1111/epi.14034. PMID: 29528488.
  27. Drane D.L., Loring D.W., Voets N.L. et al. Better object recognition and naming outcome with MRI-guided stereotactic laser amygdalohippocampotomy for temporal lobe epilepsy. Epilepsia 2015; 56:101–113. doi: 10.1111/epi.12860. PMID: 25489630.
  28. Benabid A.L., Koudsie A., Benazzouz A. et al. Deep brain stimulation of the corpus Luysi (subthalamic nucleus) and other targets in Parkinson's disease. Extension to new indications such as dystonia and epilepsy. J Neurol 2001; 248(Suppl 3) : 37–47. PMID: 11697687. 7. Cooper I.S., Upton A.R. Therapeutic implications of modulation of metabolism and functional activity of cerebral cortex by chronic stimulation of cerebellum and thalamus // Biological Psychiatry. – 1985. – V.20, N7. – P. 811-813., 13.
  29. Kerrigan J.F., Litt B., Fisher R.S. et al. Electrical stimulation of the anterior nucleus of the thalamus for the treatment of intractable epilepsy. Epilepsia 2004 ; 45: 346–354. doi: 10.1111/j.0013-9580.2004.01304.x. PMID: 15030497.
  30. Lehtimäki K., Möttönen T., Järventausta K. et al. Outcome based definition of the anterior thalamic deep brain stimulation target in refractory epilepsy. Brain Stimul 2016 ; 9 : 268-275. doi: 10.1016/j.brs.2015.09.014. PMID: 26680105.
  31. Ситников А.Р., Григорян Ю.А., Мишнякова Л.П. Стимуляция передних таламических ядер с интраоперационным микроэлектродным анализом в лечении фармакорезистентной эпилепсии. Российский нейрохирургический журнал имени профессора А.Л. Поленова 2015; VII(4): 64–72.
  32. Singhal N.S., Numis A.L., Lee M.B. et al. Responsive neuostimulation for treatment of pediatric drug-resistant epilepsy. Epilepsy Behav Case Rep 2018; 10: 21–24. doi: 10.1016/j.ebcr.2018.02.002. PMID: 30013930.
  33. Morrell M.J., RNS System in Epilepsy Study Group. Responsive cortical stimulation for the treatment of medically intractable partial epilepsy. Neurology 2011; 77: 1295–1304. doi: 10.1212/WNL.0b013e3182302056. PMID: 21917777.
  34. Bergey G.K., Morrell M.J., Mizrahi E.M. et al. Long-term treatment with responsive brain stimulation in adults with refractory partial seizures. Neurology 2015; 84: 810–817. doi: 10.1212/WNL.0000000000001280. PMID: 25616485.
  35. Gill S.J., Lukmanji S., Fiest K.M. et al. Depression screening tools in persons with epilepsy : a systematic review of validated tools. Epilepsia 2017; 58: 695–705. doi: 10.1111/epi.13651. PMID: 28064446.
  36. Helmstaedter C., Van Roost D., Clusmann H. et al. Collateral brain damage, a potential source of cognitive impairment after selective surgery for control of mesial temporal lobe epilepsy. J Neurol Neurosurg Psychiatry 2004; 75: 323–326. PMID: 14742620.
  37. Sidhu M.K., Stretton J., Winston G.P. et al. Memory fMRI predicts verbal memory decline after anterior temporal lobe resection. Neurology 2015; 84: 1512–1519. doi: 10.1212/WNL.0000000000001461. PMID: 25770199.
  38. Bonelli S.B., Thompson P.J., Yogarajah M. et al. Memory reorganization following anterior temporal lobe resection: a longitudinal functional MRI study. Brain 2013; 136(pt 6): 1889–1900. doi: 10.1093/brain/awt105. PMID: 23715092.
  39. Hoppe C., Helmstaedter C. Sensitive and specific neuropsychological assessments of the behavioral effects of epilepsy and its treatment are essential. Epilepsia 2010; 51: 2365–2366. PMID : 21192325.

Supplementary files

Supplementary Files
Action
1. JATS XML

Copyright (c) 2019 Sitnikov A.R., Skorobogatova V.A., Maslova N.N.

Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 International License.

СМИ зарегистрировано Федеральной службой по надзору в сфере связи, информационных технологий и массовых коммуникаций (Роскомнадзор).
Регистрационный номер и дата принятия решения о регистрации СМИ: серия ПИ № ФС 77-83204 от 12.05.2022.


This website uses cookies

You consent to our cookies if you continue to use our website.

About Cookies