Email this article 
Head tumors simulating the Tolosa-Hunt syndrome
- Authors: Ponomarev V.V.1, Baranowskiy A.E.1, Sytyi Y.V.1, Zaretskiy S.V.1
-
Affiliations:
- Belarusian Medical Academy of Postgraduate Education, 5th Clinical Hospital
- Issue: Vol 9, No 2 (2015)
- Pages: 10-15
- Section: Original articles
- URL: https://annaly-nevrologii.com/journal/pathID/article/view/150
- DOI: https://doi.org/10.17816/psaic150
- ID: 150
Cite item
Full Text
Abstract
The article presents the results of a clinical neuroimaging study of 15 patients with rare tumors of the head that were manifested by symptoms simulating the Tolosa-Hunt syndrome (THS).
These were primary tumors in 66.6% of the cases and metastases of breast, bronchus, prostate and melanoma cancers in 33.4% of the cases. The typical localization of these tumors, typical neurological symptoms, and their features that distinguish these cases from THS were established. In 20% of the cases, the primary
tumor site in the head in this pathology was found not to be associated with damage to the nervous system structures. The growth features in primary and metastatic tumors were specified.
Of 5 histologically proven cases, meningioma was detected in 3 patients, neuroma in 1 patient, and non-Hodgkin's lymphoma in 1 patient. We discuss indications for surgical treatment, use of a Gamma Knife, polychemotherapy, or symptomatic therapy.
Three clinical cases of primary and metastatic tumors of the head that simulated THS are described.
About the authors
V. V. Ponomarev
Belarusian Medical Academy of Postgraduate Education, 5th Clinical Hospital
Email: ponomarev@open.by
Belarus, Minsk
A. E. Baranowskiy
Belarusian Medical Academy of Postgraduate Education, 5th Clinical Hospital
Email: ponomarev@open.by
Belarus, Minsk
Yu. V. Sytyi
Belarusian Medical Academy of Postgraduate Education, 5th Clinical Hospital
Email: ponomarev@open.by
Belarus, Minsk
S. V. Zaretskiy
Belarusian Medical Academy of Postgraduate Education, 5th Clinical Hospital
Author for correspondence.
Email: ponomarev@open.by
Belarus, Minsk
References
- Гринберг М.С. Нейрохирургия. Пер. с англ. М.: МЕДпресс-информ, 2010.
- Ненашев Е.А., Кадашева А.Б. Опухоли ветвей тройничного нерва с экстракраниальным распространением. Вопр. нейрохирургии. 2013; 6: 65–70.
- Пономарев В.В. Синдром Толоза-Ханта: неврологический хамелеон. Междун. неврол. журн. 2007; 6: 78–83.
- Степанян М.А., Черекаев В.А., Кадашева А.Б. Синдромы поражения основания черепа при метастазах. Вест. неврологии, психиатрии и нейрохирургии. 2013; 8: 64–76.
- Черекаев В.А., Кушель Ю.В., Шкарубо А.Н. и др. Саркома Юинга основания черепа – первичные и метастатические опухоли: описание случаев, сравнительный анализ. Вопр. нейрохирургии.2013; 1: 30–36.
- Beraldin B.S., Felippu A., Martinelli F., Patricio H.C. Tolosa-Hunt syndrome mimicking cavernous sinus tumor. Bras. J. Otorhinolaryngol. 2013; 2: 256.
- Colnaghi S., Versino M., Marchioni E. et al. A prospective multicentre study to evaluate the consistency of the IHS diagnostic criteria, the usefulness of brain MRI for the diagnosis, follow-up and treatment management, and the outcome after high dosage 6-methylprednisolone therapy in subjects with Tolosa-Hunt syndrome. J. Headache Pain. 2010; 11: 285.
- Harnett A.N., Kemp E.G., Fraser G. Metastatic Breast Cancer Presenting as Tolosa–Hunt Syndrome. Clinical Oncology. 1999; 11: 407–409.
- McKinney A.M., Short J., Lucato L. et al. Inflammatory Myofibroblastic Tumor of the Orbit with Associated Enhancement of Meninges and Multiple Cranial Nerves. Am. J. Neuroradiol. 2006; 27: 2217–2220.
- Meningiomas (eds. Pami M., Black P., Fahebusch P.). Elsevier, 2010.
- Shengwen K, Huang S.-Y., Liu C.-Y. Extramedullary plasmocytoma masquerading as Tolosa–Hunt Syndrome. BMJ case Rep. Published online. 2009; Doi: 10.1136|bcr.2008.0804.
- Surgery of cerebello-pontine lesions. (eds. Samii M., Gerganob V.) Springer, 2013.
- Tsutsumi S., Abe Y., Yasumoto Y. et al. Metastatic skull base tumor frm thymic carcinoma mimicking Tolosa–Hunt syndrome. Neurol. Med. Chir. (Tokyo). 2010; 50: 499–502.
Supplementary files
СМИ зарегистрировано Федеральной службой по надзору в сфере связи, информационных технологий и массовых коммуникаций (Роскомнадзор).