Annals of Clinical and Experimental NeurologyAnnals of Clinical and Experimental Neurology2075-54732409-2533Research Center of Neurology42310.17816/psaic423UnknownCongenital pathological tortuosity of the internal carotid artery: population screening and genetic aspectsLobovM. A.sni@neurology.ruKаzаnchyanP. O.sni@neurology.ruIllarioshkinSergey N.<p>D. Sci. (Med.), Prof., RAS Full Member, Deputy Director for Science; Director, Brain Institute</p>sni@neurology.ruhttps://orcid.org/0000-0002-2704-6282ChechetkinAndrey O.<p>D. Sci. (Med.), Head, Ultrasound diagnostic laboratory</p>sni@neurology.ruhttps://orcid.org/0000-0002-8726-8928ValikovE. A.sni@neurology.ruSidorovaO. P.sni@neurology.ruTarаkаnоvаT. Yu.sni@neurology.ruLotarevaM. A.sni@neurology.ruBorisovaM. N.sni@neurology.ruMoscow Regional Research and Clinical Institute named after M.F. VladimirskyMONIKI named after M.V. VladimirovResearch Center of Neurology14122007145907022017Copyright © 2007, Lobov M.A., Kаzаnchyan P.O., Illarioshkin S.N., Chechetkin A.O., Valikov E.A., Sidorova O.P., Tarаkаnоvа T.Y., Lotareva M.A., Borisova M.N.2007<p>In the present work results of screening of different variants ofpathological tortuosity of internal carotids in a general childrenpopulation and in a selected group of children suffering frommigraine and migraine-like headache are presented. High prevalence of pathological tortuosity of internal carotids, includinghemodynamically significant variants of tortuosity in both investigated groups, is noted. Data of clinical, morphological,genealogical and genetic investigations confirmed hereditarydeterminancy of pathological carotid tortuosity and its interrelation with hereditary syndromal pathology of connective tissue.</p>pathological tortuosity of the internal carotid arteryscreeningduplex scanningdysplasia of connective tissueEhlers–Danlos syndromesegregation analysisпатологическая извитость внутренних сонных артерийскринингдуплексное сканированиедисплазия соединительной тканисиндром Элерса–Данлосегрегационный анализ[Деев А.С., Захарушкина И.В. Журн. неврол. и психиатрии им. С.С. Корсакова 2000; 1: 14–17.][Казанчян П.О., Валиков Е.А. Патологические деформации внутренних сонных и позвоночных артерий. М.: Медицина, 2005.][Лобов М.А. Ишемические поражения мозга при врожденных аномалиях пре- и церебральных сосудов. В сб.: Материалы Всероссийского симпозиума «Патология сосудов головы и шеи у детей и у подростков». М., 2003: 36–37.][Лелюк В.Г., Лелюк С.Э. 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