Модели гематоэнцефалического барьера in vitro: современное состояние проблемы и перспективы

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В обзоре рассматриваются существующие экспериментальные модели гематоэнцефалического барьера in vitro, применяемые для исследований проницаемости и межклеточных взаимодействий. В настоящее время для указанных целей применяются монослойные, многослойные и компьютерные модели. Первично выделенные клетки, входящие в состав моделей in vitro, могут быть мозгового и немозгового происхождения. Также используются перевиваемые линии клеток и со-культуры клеток.

Об авторах

A. В. Моргун

ГБОУ ВПО «Красноярский государственный медицинский университет им. проф. В.Ф. Войно-Ясенецкого» Минздрава России

Email: Ximikat-007@yandex.ru
Россия, Красноярск

Н. В. Кувачева

ГБОУ ВПО «Красноярский государственный медицинский университет им. проф. В.Ф. Войно-Ясенецкого» Минздрава России

Email: Ximikat-007@yandex.ru
Россия, Красноярск

Ю. K. Комлева

ГБОУ ВПО «Красноярский государственный медицинский университет им. проф. В.Ф. Войно-Ясенецкого» Минздрава России

Email: Ximikat-007@yandex.ru
Россия, Красноярск

E. A. Пожиленкова

ГБОУ ВПО «Красноярский государственный медицинский университет им. проф. В.Ф. Войно-Ясенецкого» Минздрава России

Email: Ximikat-007@yandex.ru
Россия, Красноярск

И. A. Кутищева

ГБОУ ВПО «Красноярский государственный медицинский университет им. проф. В.Ф. Войно-Ясенецкого» Минздрава России

Email: Ximikat-007@yandex.ru
Россия, Красноярск

E. С. Гагарина

ГБОУ ВПО «Красноярский государственный медицинский университет им. проф. В.Ф. Войно-Ясенецкого» Минздрава России

Автор, ответственный за переписку.
Email: Ximikat-007@yandex.ru
Россия, Красноярск

T. E. Таранушенко

ГБОУ ВПО «Красноярский государственный медицинский университет им. проф. В.Ф. Войно-Ясенецкого» Минздрава России

Email: Ximikat-007@yandex.ru
Россия, Красноярск

A. В. Озерская

ГБОУ ВПО «Красноярский государственный медицинский университет им. проф. В.Ф. Войно-Ясенецкого» Минздрава России

Email: Ximikat-007@yandex.ru
Россия, Красноярск

O. С. Окунева

ГБОУ ВПО «Красноярский государственный медицинский университет им. проф. В.Ф. Войно-Ясенецкого» Минздрава России

Email: Ximikat-007@yandex.ru
Россия, Красноярск

Алла Борисовна Салмина

ГБОУ ВПО «Красноярский государственный медицинский университет им. проф. В.Ф. Войно-Ясенецкого» Минздрава России

Email: Ximikat-007@yandex.ru
Россия, (Красноярск)

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