Роль современной нейровизуализации в изучении фокальной дистонии

Обложка


Цитировать

Полный текст

Аннотация

Представлен детальный анализ различных современных нейровизуализационных технологий, используемых для изучения патофизиологических механизмов и морфофункционального субстрата первичной фокальной дистонии (ФД). Основное внимание уделено функциональной магнитно-резонансной томографии (ФМРТ) и воксел-ориентированной морфометрии (ВОМ). Суммированы и обсуждены результаты исследований, использующих данные методы для решения задач фундаментальной неврологии и нейрофизиологии, а также для контроля эффективности проводимого лечения.

Об авторах

София Леонидовна Тимербаева

ФГБУ «Научный центр неврологии» РАМН

Автор, ответственный за переписку.
Email: sofia@neurology.ru
Россия, Москва

Список литературы

  1. Иллариошкин С.Н., Иванова-Смоленская И.А., Маркова Е.Д. ДНК-диагностика и медико-генетическое консультирование. М.: МИА, 2003.
  2. Костич В.С. Дистонические синдромы: современное состояние проблемы. В кн.: Болезнь Паркинсона и расстройства движений. Руководство для врачей (под ред. Иллариошкина С.Н., Яхно Н.Н.). М., 2008: 213–216.
  3. Маркова Е.Д. Дистонические гиперкинезы. В кн.: Экстрапирамидные расстройства. Руководство по диагностике и лечению (под. ред. Штока В.Н., Ивановой-Смоленской И.А., Левина О.С.). М.: МЕДпресс-информ, 2002: 282–290.
  4. Baker R.S., Andersen A.H., Morecraft R.J., Smith C.D. A functional magnetic resonance imaging study in patients with benign essential blepharospasm. J. Neuroophthalmol. 2003; 23: 11–15.
  5. Black K.J., Ongur D., Perlmutter J.S. Putamen volume in idiopathic focal dystonia. Neurology. 1998; 51: 819–824.
  6. Blood A.J., Flaherty A.W., Choi J.K. et al. Basal ganglia activity remains elevated after movement in focal hand dystonia. Ann. Neurol. 2004; 55: 744–748.
  7. Blood A.J., Tuch D.S., Makris N. et al. White matter abnormalities in dystonia normalize after botulinum toxin treatment.Neuro. Report. 2006; 17: 1251–1255.
  8. Bonilha L., de Vries P.M., Vincent D.J. et al. Structural white matter abnormalities in patients with idiopathic dystonia. Mov. Disord. 2007; 22: 1110–1116.
  9. Bradley D., Whelan R., Walsh R. et al. Comparing endophenotypes in adult-onset primary torsion dystonia. Mov. Disord. 2010; 25:84–90.
  10. Breakefield X.O., Blood A.J., Li Y. et al. The pathophysiological basis of dystonias. Nat Rev. Neurosci. 2008; 9(3): 222–34.
  11. Butterworth S., Francis S., Kelly E. et al. Abnormal cortical sensory activation in dystonia: an fMRI study. Mov. Disord. 2003; 18: 673–682.
  12. Ceballos-Baumann A.O., Sheean G., Passingham R.E. et al. Botulinum toxin does not reverse the cortical dysfunction associated with writer’s cramp. A PET study. Brain. 1997;120:571–582.
  13. Colosimo C., Pantano P., Calistri V. et al. Diffusion tensor imaging in primary cervical dystonia. J. Neurol. Neurosurg. Psychiatry. 2005; 76: 1591–1593.
  14. Delmaire C., Krainik A., Tezenas du M.S. et al. Disorganized somatotopy in the putamen of patients with focal hand dystonia. Neurology. 2005; 64:1391–1396.
  15. Delmaire C., Vidailhet M., Elbaz A. et al. Structural abnormalities in the cerebellum and sensorimotor circuit in writer’s cramp. Neurology. 2007; 69: 376–380.
  16. Delmaire C., Vidailhet M., Wassermann D. et al. Diffusion abnormalities in the primary sensorimotor pathways in writer’s cramp. Arch. Neurol. 2009; 66: 502–508.
  17. de Vries P.M., Johnson K.A., de Jong B.M. et al. Changed patterns of cerebral activation related to clinically normal hand movement in cervical dystonia. Clin. Neurol. Neurosurg. 2008; 110: 120–128. 53 ТЕХНОЛОГИИ Нейровизуализация при фокальной дистонии
  18. Draganski B., Thun-Hohenstein C., Bogdahn U. et al. “Motor circuit” gray matter changes in idiopathic cervical dystonia. Neurology. 2003; 61: 1228–1231.
  19. Dresel C., Haslinger B., Castrop F. et al. Silent event-related fMRI reveals deficient motor and enhanced somatosensory activation in orofacial dystonia. Brain. 2006; 129: 36–46
  20. Dresel C., Bayer F., Castro F. et al. Botulinum Toxin Modulates Basal Ganglia But Not Deficient Somatosensory Activation in Orofacial Dystonia. Mov. Disord. 2011; 26: 1496–1502.
  21. Egger K., Mueller J., Schocke M. et al. Voxel based morphometry reveals specific gray matter changes in primary dystonia. Mov. Disord. 2007; 22:1538–1542.
  22. Epidemiological Study of Dystonia in Europe (ESDE) Collaborative Group. J. Neurol. 2000; 247: 787–792.
  23. Esmaeli-Gutstein B., Nahmias C., Thompson M. et al. Positron emission tomography in patients with benign essential blepharospasm. Ophthalmic. Plast. Reconstr. Surg. 1999; 15: 23–27.
  24. Etgen T., Muhlau M., Gaser C., Sander D. Bilateral grey-matter increase in the putamen in primary blepharospasm. J. Neurol. Neurosurg. Psychiatry. 2006; 77: 1017–1020.
  25. Fabbrini G., Pantano P., Totaro P. et al. Diffusion tensor imaging in patients with primary cervical dystonia and in patients with blepharospasm. Eur. J. Neurol. 2008; 15: 185–189.
  26. Feiwell R.J., Black K.J., McGee-Minnich L.A. et al. Diminished regional cerebral blood flow response to vibration in patients with blepharospasm. Neurology. 1999; 52: 291–297.
  27. Garraux G., Bauer A., Hanakawa T. et al. Changes in brain anatomy in focal hand dystonia. Ann. Neurol. 2004; 55: 736–739.
  28. Granert O., Peller M., Gaser C. et al. Manual activity shapes structure and function in contralateral human motor hand area. Neuroimage. 2011; 54: 32–41.
  29. Granert O., Peller M., Jabusch H.C. et al. Sensorimotor skills and focal dystonia are linked to putaminal grey-matter volume in pianists. J.N.N.P. 2011; 24: 1–7.
  30. Haslinger B., Erhard P., Dresel C. et al. “Silent event-related” fMRI reveals reduced sensorimotor activation in laryngeal dystonia. Neurology. 2005; 65: 1562–1569.
  31. Hu X.Y., Wang L., Liu H., Zhang S.Z. Functional magnetic resonance imaging study of writer’s cramp. Chin. Med. J. 2006; 119: 1263–1271.
  32. Huang S.C., Carson R.E., Hoffman E.J. et al. Quantitative measurement of local cerebral blood flow in humans by positron computed tomography and 15O-water.J. Cereb. Blood Flow Metab. 1983; 3: 141–153.
  33. Hutchinson M., Nakamura T., Moeller J.R. et al. The metabolic topography of essential blepharospasm: a focal dystonia with general implications. Neurology. 2000; 55: 673–677.
  34. Ibanez V., Sadato N., Karp B. et al. Deficient activation of the motor cortical network in patients with writer’s cramp. Neurology. 1999; 53: 96–105.
  35. Islam T., Kupsch A., Bruhn H. et al. Decreased bilateral cortical representation patterns in writer’s cramp: a functional magnetic resonance imaging study at 3.0 T. Neurol. Sci. 2009; 30: 219–226.
  36. Kadota H., NakajimaY., Miyazaki M. et al. An fMRI study of musicians with focal dystonia during tapping tasks. J. Neurol. 2010; 257: 1092–8.
  37. Kerrison J.B., Lancaster J.L., Zamarripa F.E. et al. Positron emission tomography scanning in essential blepharospasm. Am. J. Ophthalmol. 2003; 136: 846–852.
  38. Leenders K., Hartvig P., Forsgren L. et al. Striatal [11C]-N-methylspiperone binding in patients with focal dystonia (torticollis) using positron emission tomography. J. Neural. Transm. Park. Dis. Dement. 1993; 5: 79–87.
  39. Lerner A., Shill H., Hanakawa T. et al. Regional cerebral blood flow correlates of the severity of writer’s cramp symptoms. Neuroimage. 2004; 21: 904–913.
  40. Magyar-Lehmann S., Antonini A., Roelcke U. et al. Cerebral glucose metabolism in patients with spasmodic torticollis. Mov. Disord. 1997; 12: 704–708.
  41. Martino D., Di Giorgio A., D’Ambrosio E. et al. Cortical gray matter changes in primary blepharospasm: A voxel-based morphometry study. Mov.Disord. 2011; 26: 1907–1912.
  42. Mori S., Zhang J. Principles of diffusion tensor imaging and its applications to basic neuroscience research. Neuron. 2006; 51: 527–539.
  43. Nahab F.B., Hallett M. Current Role of Functional MRI in the Diagnosis of Movement Disorders. Neuroimag. Clin. N. Am. 2010; 20: 103–110.
  44. Naumann M., Magyar-Lehmann S., Reiners K. et al. Sensory tricks in cervical dystonia: perceptual dysbalance of parietal cortex modulates frontal motor programming. Ann. Neurol. 2000; 47: 322–328.
  45. Nelson A.J., Blake D.T., Chen R. Digit-specific aberrations in the primary somatosensory cortex in Writer’s cramp. Ann Neurol. 2009; 66: 146-154.
  46. Obermann M., Yaldizli O., De G.A. et al. Morphometric changes of sensorimotor structures in focal dystonia. Mov. Disord. 2007; 22:1117–1123.
  47. Odergren T., Stone-Elander S., Ingvar M. Cerebral and cerebellar activation in correlation to the action-induced dystonia in writer’s cramp. Mov. Disord. 1998; 13: 497–508.
  48. Oga T., Honda M., Toma K. et al. Abnormal cortical mechanisms of voluntary muscle relaxation in patients with writer’s cramp: an fMRI study. Brain. 2002; 125: 895–903.
  49. Ogawa S., Lee T., Nayak A. et al. Oxygenation-sensitive contrast in magnetic resonance image of rodent brain at high magnetic fields. Magn. Reson. Med. 1990; 14: 68–78.
  50. Opavsky R., Hlustik P., Otruba P., Kanovsky P. Sensorimotor network in cervical dystonia and the effect of botulinum toxin treatment: A functional MRI study. J. Neurol. Sci. 2011; 306: 71–75.
  51. Pantano P., Totaro P., Fabbrini G. et al. A transverse and longitudinal MR imaging voxel-based morphometry study in patients with primary cervical dystonia. Am. J. Neuroradiol. 2011; 32: 81–84.
  52. Peller M., Zeuner K.E., Munchau A. et al. The basal ganglia are hyperactive during the discrimination of tactile stimuli in writer’s cramp. Brain. 2006; 129: 2697–2708.
  53. Perlmutter J.S., Stambuk M.K., Markham J. et al. Decreased [18F]spiperone binding in putamen in idiopathic focal dystonia. J. Neurosci. 1997; 17: 843–850. 54. Preibisch C., Berg D., Hofmann E. et al. Cerebral activation patterns in patients with writer’s cramp: a functional magnetic resonance imaging study. J.Neurol. 2001; 248: 10–17.
  54. Pujol J., Roset-Llobet J., Rosines-Cubells D. et al. Brain cortical activation during guitarinduced hand dystonia studied by functional MRI. Neuroimage. 2000; 12: 257–267.
  55. Reivich M., Kuhl D., Wolf A. et al. A model of diaschisis in the cat using middle cerebral artery occlusion. Acta Neurol. Scand. 1977; Suppl; 64:190.
  56. Roy C., Sherrington C. On the regulation of the blood supply of the brain. J. Physiol. 1890; 11: 85–108.
  57. Schmidt K.E., Linden D.E., Goebel R. et al. Striatal activation during blepharospasm revealed by fMRI. Neurology. 2003; 60: 1738–1743.
  58. Simonyan K., Ludlow C.L. Abnormal activation of the primary somatosensory cortex in spasmodic dysphonia: an fMRI study. Cereb. Cortex. 2010; 20: 2749–2759.
  59. Suzuki Y., Mizoguchi S., Kiyosawa M. et al. Glucose hypermetabolism in the thalamus of patients with essential blepharospasm. J. Neurol. 2007; 254: 890–896.
  60. Ter-Pogossian M.M., Phelps M.E., Hoffman E.J. et al. A positronemission transaxial tomograph for nuclear imaging (PETT). RadiologyRadiology. 1975; 114: 89–98.
  61. Wu C.C., Fairhall S.L., McNair N.A. et al. Impaired sensorimotor integration in focal hand dystonia patients in the absence of symptoms. J. Neurol. Neurosurg. Psychiatry. 2010; 81: 659–665.
  62. Zoons E., Booij J., Nederveen A.J. et al. Structural, functional and molecular imaging of the brain in primary focal dystonia – A review. NeuroImage. – 2011; 56: 1011–1020.

Дополнительные файлы

Доп. файлы
Действие
1. JATS XML
Скачать

© Timerbaeva S.L., 2012

Creative Commons License
Эта статья доступна по лицензии Creative Commons Attribution 4.0 International License.
СМИ зарегистрировано Федеральной службой по надзору в сфере связи, информационных технологий и массовых коммуникаций (Роскомнадзор).
Регистрационный номер и дата принятия решения о регистрации СМИ: серия ПИ № ФС 77-83204 от 12.05.2022.


Данный сайт использует cookie-файлы

Продолжая использовать наш сайт, вы даете согласие на обработку файлов cookie, которые обеспечивают правильную работу сайта.

О куки-файлах