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<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:ali="http://www.niso.org/schemas/ali/1.0/" article-type="research-article" dtd-version="1.2" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">Annals of Clinical and Experimental Neurology</journal-id><journal-title-group><journal-title xml:lang="en">Annals of Clinical and Experimental Neurology</journal-title><trans-title-group xml:lang="ru"><trans-title>Анналы клинической и экспериментальной неврологии</trans-title></trans-title-group></journal-title-group><issn publication-format="print">2075-5473</issn><issn publication-format="electronic">2409-2533</issn><publisher><publisher-name xml:lang="en">Eco-Vector</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">1144</article-id><article-id pub-id-type="doi">10.17816/ACEN.1144</article-id><article-categories><subj-group subj-group-type="toc-heading" xml:lang="en"><subject>Original articles</subject></subj-group><subj-group subj-group-type="toc-heading" xml:lang="ru"><subject>Оригинальные статьи</subject></subj-group><subj-group subj-group-type="article-type"><subject>Research Article</subject></subj-group></article-categories><title-group><article-title xml:lang="en">Accelerometry in Diagnosis of Functional Tremor</article-title><trans-title-group xml:lang="ru"><trans-title>Акселерометрический анализ в диагностике функционального тремора</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-6217-4151</contrib-id><name-alternatives><name xml:lang="en"><surname>Evdokimov</surname><given-names>Konstantin M.</given-names></name><name xml:lang="ru"><surname>Евдокимов</surname><given-names>Константин Михайлович</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>postgraduate student, neurologist, 5th Neurology department, Institute of Clinical and Preventive Neurology</p></bio><bio xml:lang="ru"><p>аспирант, врач-невролог 5-го неврологического отделения с молекулярно-генетической лабораторией Института клинической и профилактической неврологии</p></bio><email>evdokimov@neurology.ru</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-3337-1759</contrib-id><name-alternatives><name xml:lang="en"><surname>Ivanova</surname><given-names>Ekaterina O.</given-names></name><name xml:lang="ru"><surname>Иванова</surname><given-names>Екатерина Олеговна</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>Cand. Sci. (Med.), researcher, neurologist, 5th Neurology department, Institute of Clinical and Preventive Neurology</p></bio><bio xml:lang="ru"><p>канд. мед. наук, н. с., врач-невролог 5-го неврологического отделения с молекулярно-генетической лабораторией Института клинической и профилактической неврологии</p></bio><email>evdokimov@neurology.ru</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-6381-2925</contrib-id><name-alternatives><name xml:lang="en"><surname>Brutyan</surname><given-names>Amayak G.</given-names></name><name xml:lang="ru"><surname>Брутян</surname><given-names>Амаяк Грачевич</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>Cand. Sci. (Med.), Head, Laboratory of clinical neurophysiology, Institute of Clinical and Preventive Neurology</p></bio><bio xml:lang="ru"><p>канд. мед. наук, в. н. с., рук. лаб. клинической нейрофизиологии Института клинической и профилактической неврологии</p></bio><email>evdokimov@neurology.ru</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-8070-7644</contrib-id><name-alternatives><name xml:lang="en"><surname>Fedotova</surname><given-names>Ekaterina Y.</given-names></name><name xml:lang="ru"><surname>Федотова</surname><given-names>Екатерина Юрьевна</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>D. Sci. (Med.), leading researcher, Head, 5th Neurology department, Institute of Clinical and Preventive Neurology</p></bio><bio xml:lang="ru"><p>д-р мед. наук, в. н. с., зав. 5-м неврологическим отделением Института клинической и профилактической неврологии</p></bio><email>evdokimov@neurology.ru</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-2704-6282</contrib-id><name-alternatives><name xml:lang="en"><surname>Illarioshkin</surname><given-names>Sergey N.</given-names></name><name xml:lang="ru"><surname>Иллариошкин</surname><given-names>Сергей Николаевич</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>D. Sci. (Med.), prof., RAS Full Member, Director, Brain Institute, Deputy director</p></bio><bio xml:lang="ru"><p>д-р мед. наук, проф., акад. РАН, зам. директора по научной работе, директор Института мозга</p></bio><email>evdokimov@neurology.ru</email><xref ref-type="aff" rid="aff1"/></contrib></contrib-group><aff-alternatives id="aff1"><aff><institution xml:lang="en">Research Center of Neurology</institution></aff><aff><institution xml:lang="ru">Научный центр неврологии</institution></aff></aff-alternatives><pub-date date-type="pub" iso-8601-date="2024-12-06" publication-format="electronic"><day>06</day><month>12</month><year>2024</year></pub-date><volume>18</volume><issue>4</issue><issue-title xml:lang="en"/><issue-title xml:lang="ru"/><fpage>5</fpage><lpage>11</lpage><history><date date-type="received" iso-8601-date="2024-05-31"><day>31</day><month>05</month><year>2024</year></date><date date-type="accepted" iso-8601-date="2024-07-02"><day>02</day><month>07</month><year>2024</year></date></history><permissions><copyright-statement xml:lang="en">Copyright ©; 2024, Evdokimov K.M., Ivanova E.O., Brutyan A.G., Fedotova E.Y., Illarioshkin S.N.</copyright-statement><copyright-statement xml:lang="ru">Copyright ©; 2024, Евдокимов К.М., Иванова Е.О., Брутян А.Г., Федотова Е.Ю., Иллариошкин С.Н.</copyright-statement><copyright-year>2024</copyright-year><copyright-holder xml:lang="en">Evdokimov K.M., Ivanova E.O., Brutyan A.G., Fedotova E.Y., Illarioshkin S.N.</copyright-holder><copyright-holder xml:lang="ru">Евдокимов К.М., Иванова Е.О., Брутян А.Г., Федотова Е.Ю., Иллариошкин С.Н.</copyright-holder><ali:free_to_read xmlns:ali="http://www.niso.org/schemas/ali/1.0/"/><license><ali:license_ref xmlns:ali="http://www.niso.org/schemas/ali/1.0/">https://creativecommons.org/licenses/by/4.0</ali:license_ref></license></permissions><self-uri xlink:href="https://annaly-nevrologii.com/pathID/article/view/1144">https://annaly-nevrologii.com/pathID/article/view/1144</self-uri><abstract xml:lang="en"><p>Introduction. Functional tremor (FT) is the most common phenotype of functional movement disorders. Electrophysiological assessment is included in the diagnostic criteria for tremor; however, there is currently no consensus criteria for the differential diagnosis of FT.</p> <p>The objective of this study was to evaluate the utility of tremor frequency characteristics derived from accelerometry for the differential diagnosis between FT and organic tremor (OT).</p> <p>Materials and methods. Nineteen patients with FT, 20 patients with essential tremor, and 20 patients with Parkinson's disease were enrolled in the study and underwent electrophysiological examination with a two-channel accelerometer and subsequent data processing.</p> <p>Results. The study results revealed the differences in the frequency peak widths in patients with FT and OT, predominantly while performing a cognitive load task. This criterion showed a high sensitivity (100%) and a high specificity (97.5%) for the diagnosis of FT in the study population.</p> <p>Conclusion. Tremor characteristics recorded during accelerometry combined with cognitive load task can serve as an additional testing aid for differential diagnosis between functional and organic tremor.</p></abstract><trans-abstract xml:lang="ru"><p>Введение. Функциональный тремор (ФТ) — наиболее часто встречающийся фенотип функционального двигательного расстройства. Электрофизиологическая оценка тремора входит в объём диагностики, однако нет единого стандарта дифференциальной диагностики ФТ.</p> <p>Целью данного исследования являлась оценка возможности использования частотных характеристик тремора по данным акселерометрии для дифференциальной диагностики ФТ и органического тремора (ОТ).</p> <p>Материалы и методы. В исследовании участвовали 19 пациентов с ФТ, 20 пациентов с эссенциальным тремором и 20 пациентов с болезнью Паркинсона, которым проводили электрофизиологическое исследование, включающее двухканальную акселерометрию с последующей обработкой полученных данных.</p> <p>Результаты. В ходе исследования были выявлены различия в ширине частотного пика тремора по данным акселерометрии у пациентов с ФТ и ОТ, преимущественно на фоне когнитивной нагрузки. Данный показатель в исследуемой выборке продемонстрировал высокую чувствительность (100%) и специфичность (97,5%) для диагностики ФТ.</p> <p>Заключение. Анализ характеристик тремора по данным акселерометрии с дополнительной задачей в виде когнитивной нагрузки может использоваться в качестве дополнительного теста для дифференциальной диагностики ФТ и ОТ.</p></trans-abstract><kwd-group xml:lang="en"><kwd>functional movement disorders</kwd><kwd>functional tremor</kwd><kwd>diagnosis</kwd><kwd>accelerometry</kwd></kwd-group><kwd-group xml:lang="ru"><kwd>функциональные двигательные расстройства</kwd><kwd>функциональный тремор</kwd><kwd>диагностика</kwd><kwd>акселерометрия</kwd></kwd-group><funding-group/></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><mixed-citation>Иллариошкин С.Н., Иванова-Смоленская И.А. Дрожательные гиперкинезы. Руководство для врачей. М.; 2011. Illarioshkin S.N., Ivanova-Smolenskaya I.A. Trembling hyperkinesis. Guide for doctors. Moscow; 2011. (In Russ.)</mixed-citation></ref><ref id="B2"><label>2.</label><mixed-citation>Bhatia K.P., Bain P., Bajaj N. et al. 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