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<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:ali="http://www.niso.org/schemas/ali/1.0/" article-type="research-article" dtd-version="1.2" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">Annals of Clinical and Experimental Neurology</journal-id><journal-title-group><journal-title xml:lang="en">Annals of Clinical and Experimental Neurology</journal-title><trans-title-group xml:lang="ru"><trans-title>Анналы клинической и экспериментальной неврологии</trans-title></trans-title-group></journal-title-group><issn publication-format="print">2075-5473</issn><issn publication-format="electronic">2409-2533</issn><publisher><publisher-name xml:lang="en">Eco-Vector</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">1145</article-id><article-id pub-id-type="doi">10.17816/ACEN.1145</article-id><article-categories><subj-group subj-group-type="toc-heading" xml:lang="en"><subject>Clinical analysis</subject></subj-group><subj-group subj-group-type="toc-heading" xml:lang="ru"><subject>Клинический разбор</subject></subj-group><subj-group subj-group-type="article-type"><subject>Research Article</subject></subj-group></article-categories><title-group><article-title xml:lang="en">Thromboembolic cerebral aneurysms</article-title><trans-title-group xml:lang="ru"><trans-title>Тромбоэмболический тип течения церебральных аневризм</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-6321-4557</contrib-id><name-alternatives><name xml:lang="en"><surname>Shnyakin</surname><given-names>Pavel G.</given-names></name><name xml:lang="ru"><surname>Шнякин</surname><given-names>Павел Геннадьевич</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>Dr. Sci. (Med.), Professor, Head, Department of traumatology, orthopedics and neurosurgery with a postgraduate course, Prof. V.F. Voino-Yasenetsky Krasnoyarsk State Medical University; Head, Regional vascular center, Krasnoyarsk Regional Clinical Hospital</p></bio><bio xml:lang="ru"><p>д-р мед. наук, профессор, зав. каф. травматологии, ортопедии и нейрохирургии с курсом ПО КрасГМУ им. проф. В.Ф. Войно-Ясенецкого; руководитель регионального сосудистого центра Краевой клинической больницы</p></bio><email>anna-gavrilova20@yandex.ru</email><xref ref-type="aff" rid="aff1"/><xref ref-type="aff" rid="aff2"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0009-0003-9533-9364</contrib-id><name-alternatives><name xml:lang="en"><surname>Roslavtseva</surname><given-names>Valeria V.</given-names></name><name xml:lang="ru"><surname>Рославцева</surname><given-names>Валерия Владимировна</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>neurologist, 2<sup>nd</sup> Neurosurgical department</p></bio><bio xml:lang="ru"><p>врач-невролог нейрохирургического отделения </p></bio><email>anna-gavrilova20@yandex.ru</email><xref ref-type="aff" rid="aff2"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0009-0000-4511-5774</contrib-id><name-alternatives><name xml:lang="en"><surname>Gavrilova</surname><given-names>Anna O.</given-names></name><name xml:lang="ru"><surname>Гаврилова</surname><given-names>Анна Олеговна</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>student, Faculty of medicine</p></bio><bio xml:lang="ru"><p>студентка 5-го курса лечебного факультета</p></bio><email>anna-gavrilova20@yandex.ru</email><xref ref-type="aff" rid="aff1"/></contrib></contrib-group><aff-alternatives id="aff1"><aff><institution xml:lang="en">Professor V.F. Voino-Yasenetsky Krasnoyarsk State Medical University</institution></aff><aff><institution xml:lang="ru">Красноярский государственный медицинский университет имени профессора В.Ф. Войно-Ясенецкого</institution></aff></aff-alternatives><aff-alternatives id="aff2"><aff><institution xml:lang="en">Krasnoyarsk Regional Clinical Hospital</institution></aff><aff><institution xml:lang="ru">Краевая клиническая больница</institution></aff></aff-alternatives><pub-date date-type="pub" iso-8601-date="2025-03-15" publication-format="electronic"><day>15</day><month>03</month><year>2025</year></pub-date><volume>19</volume><issue>1</issue><issue-title xml:lang="en"/><issue-title xml:lang="ru"/><fpage>85</fpage><lpage>92</lpage><history><date date-type="received" iso-8601-date="2024-06-03"><day>03</day><month>06</month><year>2024</year></date><date date-type="accepted" iso-8601-date="2024-07-15"><day>15</day><month>07</month><year>2024</year></date></history><permissions><copyright-statement xml:lang="en">Copyright ©; 2025, Shnyakin P.G., Roslavtseva V.V., Gavrilova A.O.</copyright-statement><copyright-statement xml:lang="ru">Copyright ©; 2025, Шнякин П.Г., Рославцева В.В., Гаврилова А.О.</copyright-statement><copyright-year>2025</copyright-year><copyright-holder xml:lang="en">Shnyakin P.G., Roslavtseva V.V., Gavrilova A.O.</copyright-holder><copyright-holder xml:lang="ru">Шнякин П.Г., Рославцева В.В., Гаврилова А.О.</copyright-holder><ali:free_to_read xmlns:ali="http://www.niso.org/schemas/ali/1.0/"/><license><ali:license_ref xmlns:ali="http://www.niso.org/schemas/ali/1.0/">https://creativecommons.org/licenses/by/4.0</ali:license_ref></license></permissions><self-uri xlink:href="https://annaly-nevrologii.com/pathID/article/view/1145">https://annaly-nevrologii.com/pathID/article/view/1145</self-uri><abstract xml:lang="en"><p>Intracranial hemorrhage is the most common outcome of cerebral aneurysms, and, therefore, clinical guidelines for the management of patients with cerebral aneurysms are primarily based on assessing the risk of their rupture. Brain ischemia due to the cerebral aneurysms occur significantly less frequently (i.e. in 3–5% of cases), and, in most cases, it is caused by distal embolism with thrombotic masses from large and giant thrombosed aneurysms. A conclusion that ischemic stroke is associated with embolism of thrombi from the aneurysm sac can be made only after ruling out other risk factors, primarily cardioembolism and stenosis of intracranial and extracranial arteries. The management of patients with thromboembolism from aneurysms who developed ischemia is challenging because these patients require antithrombotic agents, which can result in recanalization and rupture of the aneurysm. In addition, the optimal timing for surgery for the aneurysm in the event of acute ischemia has not been determined, given the high risk of recurrent embolism and aneurysm rupture. We present an overview of recent studies on this issue and our experience in managing 4 patients with thromboembolic stroke caused by cerebral aneurysms.</p></abstract><trans-abstract xml:lang="ru"><p>Геморрагический тип течения церебральных аневризм встречается наиболее часто, в связи с чем клинические рекомендации по ведению пациентов с аневризмами головного мозга в первую очередь основываются на оценке риска их разрыва. Ишемический тип течения церебральных аневризм встречается значимо реже (в 3–5% случаев) и чаще всего связан с дистальной эмболией тромботических масс из больших и гигантских тромбированных аневризм. Сделать заключение о том, что ишемический инсульт ассоциирован с эмболией тромбов из мешка аневризмы, можно только при исключении других факторов риска, в первую очередь кардиоэмболии и стенозов интра- и экстракраниальных артерий. Имеются сложности в определении тактики ведения пациентов с тромбоэмболией из аневризм и развитием ишемии, т. к. требуется назначение антитромботических препаратов, которые могут способствовать реканализации аневризмы и её разрыву. Кроме того, в настоящее время не определены оптимальные сроки для выполнения хирургического вмешательства на аневризме при развитии острой ишемии, учитывая высокий риск повторных эпизодов эмболии, а также риск разрыва аневризмы. В статье представлены краткий обзор современных исследований по данной проблеме и собственный опыт ведения 4 пациентов с тромбоэмболическим вариантом течения церебральных аневризм.</p></trans-abstract><kwd-group xml:lang="en"><kwd>cerebral aneurysm</kwd><kwd>ischemic stroke</kwd><kwd>embolism</kwd><kwd>thrombosis</kwd></kwd-group><kwd-group xml:lang="ru"><kwd>церебральная аневризма</kwd><kwd>ишемический инсульт</kwd><kwd>эмболия</kwd><kwd>тромбоз</kwd></kwd-group><funding-group/></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><mixed-citation>Крылов В.В., Шатохин Т.А., Шетова И.М. и др. Российское исследование по хирургии аневризм головного мозга (РИХА II). Вопросы нейрохирургии им. Н.Н. Бурденко. 2024;88(1):7–20. Krylov VV, Shatokhin TA, Shetova IM, et al. Russian research on surgery of brain aneurysms (RRSA II). Burdenko’s Journal of Neurosurgery. 2024;88(1):7–20. 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