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<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:ali="http://www.niso.org/schemas/ali/1.0/" article-type="other" dtd-version="1.2" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">Annals of Clinical and Experimental Neurology</journal-id><journal-title-group><journal-title xml:lang="en">Annals of Clinical and Experimental Neurology</journal-title><trans-title-group xml:lang="ru"><trans-title>Анналы клинической и экспериментальной неврологии</trans-title></trans-title-group></journal-title-group><issn publication-format="print">2075-5473</issn><issn publication-format="electronic">2409-2533</issn><publisher><publisher-name xml:lang="en">Eco-Vector</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">180</article-id><article-id pub-id-type="doi">10.17816/psaic180</article-id><article-categories><subj-group subj-group-type="toc-heading" xml:lang="en"><subject>Reviews</subject></subj-group><subj-group subj-group-type="toc-heading" xml:lang="ru"><subject>Обзоры</subject></subj-group><subj-group subj-group-type="article-type"><subject>Unknown</subject></subj-group></article-categories><title-group><article-title xml:lang="en">Reproductive health of women with multiple sclerosis</article-title><trans-title-group xml:lang="ru"><trans-title>Репродуктивное здоровье женщин, больных рассеянным склерозом</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Tikhonovskaya</surname><given-names>O. A.</given-names></name><name xml:lang="ru"><surname>Тихоновская</surname><given-names>O. A.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><email>tikhonovskaya2012@mail.ru</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Pinchuk</surname><given-names>A. Y.</given-names></name><name xml:lang="ru"><surname>Пинчук</surname><given-names>A. Ю.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><email>tikhonovskaya2012@mail.ru</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Alifirova</surname><given-names>V. M.</given-names></name><name xml:lang="ru"><surname>Алифирова</surname><given-names>В. M.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><email>tikhonovskaya2012@mail.ru</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Musina</surname><given-names>N. F.</given-names></name><name xml:lang="ru"><surname>Мусина</surname><given-names>Н. Ф.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><email>tikhonovskaya2012@mail.ru</email><xref ref-type="aff" rid="aff1"/></contrib></contrib-group><aff-alternatives id="aff1"><aff><institution xml:lang="en">Siberian State Medical University</institution></aff><aff><institution xml:lang="ru">Сибирский государственный медицинский университет Минздрава России</institution></aff></aff-alternatives><pub-date date-type="pub" iso-8601-date="2014-06-09" publication-format="electronic"><day>09</day><month>06</month><year>2014</year></pub-date><volume>8</volume><issue>2</issue><issue-title xml:lang="en"/><issue-title xml:lang="ru"/><fpage>46</fpage><lpage>50</lpage><history><date date-type="received" iso-8601-date="2017-02-01"><day>01</day><month>02</month><year>2017</year></date></history><permissions><copyright-statement xml:lang="en">Copyright ©; 2014, Tikhonovskaya O.A., Pinchuk A.Y., Alifirova V.M., Musina N.F.</copyright-statement><copyright-statement xml:lang="ru">Copyright ©; 2014, Tikhonovskaya O.A., Pinchuk A.Y., Alifirova V.M., Musina N.F.</copyright-statement><copyright-year>2014</copyright-year><copyright-holder xml:lang="en">Tikhonovskaya O.A., Pinchuk A.Y., Alifirova V.M., Musina N.F.</copyright-holder><copyright-holder xml:lang="ru">Tikhonovskaya O.A., Pinchuk A.Y., Alifirova V.M., Musina N.F.</copyright-holder><ali:free_to_read xmlns:ali="http://www.niso.org/schemas/ali/1.0/"/><license><ali:license_ref xmlns:ali="http://www.niso.org/schemas/ali/1.0/">https://creativecommons.org/licenses/by/4.0</ali:license_ref></license></permissions><self-uri xlink:href="https://annaly-nevrologii.com/pathID/article/view/180">https://annaly-nevrologii.com/pathID/article/view/180</self-uri><abstract xml:lang="en"><p>Organic diseases of the central nervous system (CNS) are of utmost importance in the formation of gynecological pathology. Multiple sclerosis (MS) and mmunomodifying therapy which is in use in patients with this disease have a significant effect on menstrual and reproductive functions, pregnancy and delivery in women with MS. Infertility in patients with MS is due, on the one hand, to psychological and sexual problems and, on the other hand, to the secondary gonadal failure. Obstetric outcomes in women with MS do not differ significantly from those in the general population, but some specific characteristics of the course of pregnancy and delivery need attention and multidisciplinary approach.</p></abstract><trans-abstract xml:lang="ru"><p>Немаловажное значение в формировании гинекологической патологии имеют органические заболевания центральной нервной системы ЦНС). Рассеянный склероз (РС) и иммуномодулирующая терапия, применяемая у пациентов с данным заболеванием, оказывают значительное влияние на менструальную и репродуктивную функции, течение беременности и родов. Бесплодие у пациентов с РС обусловлено, с одной стороны, психологическими и сексуальными проблемами, с другой – формированием вторичной недостаточности гонад. Акушерские исходы у женщин с РС значимо не отличаются от таковых в общей популяции, но некоторые особенности течения беременности и родов заслуживают внимания и требуют междисциплинарного подхода.</p></trans-abstract><kwd-group xml:lang="en"><kwd>multiple sclerosis</kwd><kwd>fertility</kwd><kwd>pregnancy, delivery</kwd><kwd>immunomodifying therapy</kwd></kwd-group><kwd-group xml:lang="ru"><kwd>рассеянный склероз</kwd><kwd>фертильность</kwd><kwd>беременность</kwd><kwd>роды</kwd><kwd>иммуномодулирующая терапия</kwd></kwd-group><funding-group/></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><mixed-citation>Белова А.Н., Качалина Т.С., Крупин В.Н. и др. Рассеянный склероз и беременность. Неврол. журн. 2010; 6: 4–10.</mixed-citation></ref><ref id="B2"><label>2.</label><mixed-citation>Кучерова И.В. 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