Annals of Clinical and Experimental NeurologyAnnals of Clinical and Experimental NeurologyАнналы клинической и экспериментальной неврологии2075-54732409-2533Eco-Vector30210.17816/psaic302Original articlesОригинальные статьиUnknownFunctional MRI study: passive motor paradigm in the assessment of sensorimotor systemИспользование пассивной двигательной парадигмы в оценке сенсомоторной системы методом функциональной МРТhttps://orcid.org/0000-0001-9929-2725DobryninaLarisa A.ДобрынинаЛариса Анатольевна
Russian Federation

D. Sci. (Med.), Head, 3rd Neurology department

д.м.н., г.н.с., рук. 3-го неврологического отделения

dobrla@mail.ruhttps://orcid.org/0000-0001-9396-6063KremnevaElena I.КремневаЕлена Игоревна
Russian Federation

Cand. Sci. (Med.), senior researcher, Radiology department

к.м.н., с.н.с. отд. нейровизуализации

dobrla@mail.ruhttps://orcid.org/0000-0001-5539-245XKonovalovRodion N.КоноваловРодион Николаевич
Russian Federation

Cand. Sci. (Med.), senior researcher, Neuroradiology department

к.м.н., с.н.с. отд. лучевой диагностики

dobrla@mail.ruhttps://orcid.org/0000-0001-7491-7215KadykovAlbert S.КадыковАльберт Серафимович
Russian Federation

D. Sci. (Med.), Professor, senior researcher, 3rd Neurological department

д.м.н., проф., г.н.с. 3-го неврологического отделения

dobrla@mail.ruResearch Center of NeurologyФГБНУ «Научный центр неврологии»1309201153111903022017Copyright ©; 2011, Dobrynina L.A., Kremneva E.I., Konovalov R.N., Kadykov A.S.Copyright ©; 2011, Dobrynina L.A., Kremneva E.I., Konovalov R.N., Kadykov A.S.2011Dobrynina L.A., Kremneva E.I., Konovalov R.N., Kadykov A.S.Dobrynina L.A., Kremneva E.I., Konovalov R.N., Kadykov A.S.https://creativecommons.org/licenses/by/4.0https://annaly-nevrologii.com/pathID/article/view/302

The fMRI study of 7 healthy volunteers was performed to evaluate the neuron networks of sensorimotor system during active and passive movements of the left and right index fingers. While performing all the tasks, the predominant activation of primary sensorimotor, premotor, supplementary motor areas, secondary sensory zones were shown on the contralateral side, as well as ipsilateral cerebellar activation. It was demonstrated that brain activation areas in both types of paradigm were corresponding, as well as the activation clusters size, amplitude and voxel coordinates, with the maximum values in the primary motor and sensory cortex. These results allow recommending the paradigm of passive index finger movements in given rate for the evaluation of sensorimotor system in patients with movement disorders.

Было проведено исследование нейрональных сетей сенсомоторной системы семи здоровых добровольцев при выполнении активных и пассивных движений правым и левым указательным пальцем в заданном темпе методом функциональной МРТ (фМРТ). При обработке полученных данных для обеих парадигм было выявлено доминирование активации первичной сенсомоторной, премоторной, дополнительной моторной коры, вторичных сенсорных зон на стороне, противоположной движению, а также активации в полушарии мозжечка, соответствующем стороне движения. Было показано совпадение зон региональной активации, а также объема активации, амплитуды и координат вокселов с максимальными значениями в первичной моторной и сенсорной коре. Полученные данные позволяют использовать пассивные движения наряду с активными для исследования сенсомоторной коры и рекомендовать парадигму пассивных движений указательным пальцем в заданном темпе для исследования сенсомоторной системы больных с двигательными нарушениями.

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