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<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:ali="http://www.niso.org/schemas/ali/1.0/" article-type="other" dtd-version="1.2" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">Annals of Clinical and Experimental Neurology</journal-id><journal-title-group><journal-title xml:lang="en">Annals of Clinical and Experimental Neurology</journal-title><trans-title-group xml:lang="ru"><trans-title>Анналы клинической и экспериментальной неврологии</trans-title></trans-title-group></journal-title-group><issn publication-format="print">2075-5473</issn><issn publication-format="electronic">2409-2533</issn><publisher><publisher-name xml:lang="en">Eco-Vector</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">357</article-id><article-id pub-id-type="doi">10.17816/psaic357</article-id><article-categories><subj-group subj-group-type="toc-heading" xml:lang="en"><subject>Technologies</subject></subj-group><subj-group subj-group-type="toc-heading" xml:lang="ru"><subject>Технологии</subject></subj-group><subj-group subj-group-type="article-type"><subject>Unknown</subject></subj-group></article-categories><title-group><article-title xml:lang="en">Method of wavelet transform in neurology: analysis of time and frequency characteristics of typical and atypical discharges of nonconvulsive epilepsy</article-title><trans-title-group xml:lang="ru"><trans-title>Метод вейвлет-преобразования в неврологии: анализ частотно-временных характеристик типичных и атипичных разрядов неконвульсивной эпилепсии</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Gabova</surname><given-names>A. V.</given-names></name><name xml:lang="ru"><surname>Габова</surname><given-names>A. В.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><email>agabova@yandex.ru</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Kusnetsova</surname><given-names>G. D.</given-names></name><name xml:lang="ru"><surname>Кузнецова</surname><given-names>Г. Д.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><email>agabova@yandex.ru</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Gnezditsky</surname><given-names>V. V.</given-names></name><name xml:lang="ru"><surname>Гнездицкий</surname><given-names>В. В.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><email>agabova@yandex.ru</email><xref ref-type="aff" rid="aff2"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Bazyan</surname><given-names>A. S.</given-names></name><name xml:lang="ru"><surname>Базян</surname><given-names>A. С.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><email>agabova@yandex.ru</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Obukhov</surname><given-names>Yu. V.</given-names></name><name xml:lang="ru"><surname>Обухов</surname><given-names>Ю. В.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><email>agabova@yandex.ru</email><xref ref-type="aff" rid="aff3"/></contrib></contrib-group><aff-alternatives id="aff1"><aff><institution xml:lang="en">Institute of Higher Nervous Activity and Neurophysiology, Russian Academy of Medical Sciences</institution></aff><aff><institution xml:lang="ru">Институт высшей нервной деятельности и нейрофизиологии РАН</institution></aff></aff-alternatives><aff-alternatives id="aff2"><aff><institution xml:lang="en">Research Center of Neurology</institution></aff><aff><institution xml:lang="ru">ФГБНУ «Научный центр неврологии»</institution></aff></aff-alternatives><aff-alternatives id="aff3"><aff><institution xml:lang="en">Institute of Radioengineering and Electronics, Russian Academy of Sciences</institution></aff><aff><institution xml:lang="ru">Институт радиотехники и электроники РАН</institution></aff></aff-alternatives><pub-date date-type="pub" iso-8601-date="2009-12-14" publication-format="electronic"><day>14</day><month>12</month><year>2009</year></pub-date><volume>3</volume><issue>4</issue><issue-title xml:lang="en"/><issue-title xml:lang="ru"/><fpage>39</fpage><lpage>44</lpage><history><date date-type="received" iso-8601-date="2017-02-06"><day>06</day><month>02</month><year>2017</year></date></history><permissions><copyright-statement xml:lang="en">Copyright ©; 2009, Gabova A.V., Kusnetsova G.D., Gnezditskii V.V., Bazyan A.S., Obukhov Y.V.</copyright-statement><copyright-statement xml:lang="ru">Copyright ©; 2009, Gabova A.V., Kusnetsova G.D., Gnezditskii V.V., Bazyan A.S., Obukhov Y.V.</copyright-statement><copyright-year>2009</copyright-year><copyright-holder xml:lang="en">Gabova A.V., Kusnetsova G.D., Gnezditskii V.V., Bazyan A.S., Obukhov Y.V.</copyright-holder><copyright-holder xml:lang="ru">Gabova A.V., Kusnetsova G.D., Gnezditskii V.V., Bazyan A.S., Obukhov Y.V.</copyright-holder><ali:free_to_read xmlns:ali="http://www.niso.org/schemas/ali/1.0/"/><license><ali:license_ref xmlns:ali="http://www.niso.org/schemas/ali/1.0/">https://creativecommons.org/licenses/by/4.0</ali:license_ref></license></permissions><self-uri xlink:href="https://annaly-nevrologii.com/pathID/article/view/357">https://annaly-nevrologii.com/pathID/article/view/357</self-uri><abstract xml:lang="en"><p> </p><p>Timefrequency dynamics and spatial characteristics of dischar ges of different types in patients with nonconvulsive epilepsy (n=23) were investigated. Modified wavelet transform was used for the analysis. In patients (n=11) with the diagnosis of childhood absence epilepsy, juvenile absence epilepsy or juveni le mioclonic epilepsy, the timefrequency dynamics of spikewa ve discharges were identical. Typical spikewave discharge arose in the frontal cortex with the short period of maximal frequency (5–6 Hz). The further frequency was 3–3.5 Hz with periodical (about 1 s) fluctuations. In another group of patients (n=12) with the diagnosis of nonconvulsive epilepsy the discharges of several types were observed, and they differed in duration, time frequency dynamics and activity localization with maximal amplitude in the cortex. Atypical discharges were different from typical ones: they had less ordered timefrequency structure and lacked the high frequency period in the frontal cortex. In some patients typical and atypical discharges, or two different forms of atypical discharges could be seen on the same EEG record. The obtained data show that the discharges’ timefrequency analysis with the help of the modified wavelet transform can be used for the classification of discharges of different types and are of value for differential diagnosis of nonconvulsive epilepsy.</p>  <p> </p> <p> </p></abstract><trans-abstract xml:lang="ru"><p>Исследовали частотно-временную динамику и пространственные особенности разрядов разного типа у пациентов с неконвульсивной эпилепсией (n=23). Для анализа использовали модифицированное вейвлет-преобразование. У пациентов (n=11) с диагнозом детской абсансной эпилепсии, юношеской абсансной или юношеской миоклонической эпилепсии частотно-временная структура разрядов пик-волна была идентичной. Типичный разряд пик-волна возникал в лобной области коры с короткого периода максимальной частоты (5–6 Гц). Дальнейшая частота была 3–3,5 Гц и колебалась с периодом около 1 с. У другой группы пациентов (n=12) с диагнозом неконвульсивной эпилепсии в ЭЭГ наблюдались разряды нескольких типов, различающиеся по длительности, частотно-временной динамике и локализации в коре активности с максимальной амплитудой. Атипичные разряды отличались от типичных менее упорядоченной частотно-временной структурой и отсутствием в лобной коре периода увеличенной частоты в начале разряда. У ряда пациентов в ЭЭГ могли одновременно присутствовать типичные и атипичные разряды или две разные формы атипичных разрядов. Полученные данные показывают, что анализ частотно-временной структуры разрядов c помощью модифицированного преобразования вейвлет может использоваться для классификации разрядов разного типа и быть полезным при дифференциальной диагностикенеконвульсивной эпилепсии.</p></trans-abstract><kwd-group xml:lang="en"><kwd>nonconvulsive epilepsy</kwd><kwd>typical and atypical discharges time</kwd><kwd>frequency analysis</kwd><kwd>wavelet transform</kwd></kwd-group><kwd-group xml:lang="ru"><kwd>неконвульсивная эпилепсия</kwd><kwd>типичные и атипичные разряды</kwd><kwd>частотно-временной анализ</kwd><kwd>вейвлет-преобразование</kwd></kwd-group><funding-group/></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><mixed-citation>Габова А.В., Боснякова Д.Ю., Босняков М.С. и др. Частотно-временная структура разрядов пикволна генетической абсансной эпилепсии. Докл. Акад. 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