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<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:ali="http://www.niso.org/schemas/ali/1.0/" article-type="other" dtd-version="1.2" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">Annals of Clinical and Experimental Neurology</journal-id><journal-title-group><journal-title xml:lang="en">Annals of Clinical and Experimental Neurology</journal-title><trans-title-group xml:lang="ru"><trans-title>Анналы клинической и экспериментальной неврологии</trans-title></trans-title-group></journal-title-group><issn publication-format="print">2075-5473</issn><issn publication-format="electronic">2409-2533</issn><publisher><publisher-name xml:lang="en">Eco-Vector</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">677</article-id><article-id pub-id-type="doi">10.25692/ACEN.2020.3.1</article-id><article-categories><subj-group subj-group-type="toc-heading" xml:lang="en"><subject>Original articles</subject></subj-group><subj-group subj-group-type="toc-heading" xml:lang="ru"><subject>Оригинальные статьи</subject></subj-group><subj-group subj-group-type="article-type"><subject>Unknown</subject></subj-group></article-categories><title-group><article-title xml:lang="en">The World Stroke Organization’s Declaration for worldwide primary stroke and dementia prevention</article-title><trans-title-group xml:lang="ru"><trans-title>Декларация по глобальной первичной профилактике инсульта и деменции Всемирной организации по борьбе с инсультом</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><name><surname>Brainin</surname><given-names>Michael</given-names></name><address><country country="AT">Austria</country></address><email>valery.feigin@aut.ac.nz</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name><surname>Feigin</surname><given-names>Valery l</given-names></name><address><country country="NZ">New Zealand</country></address><email>valery.feigin@aut.ac.nz</email><xref ref-type="aff" rid="aff2"/></contrib><contrib contrib-type="author"><name><surname>Norrving</surname><given-names>Bo</given-names></name><address><country country="SE">Sweden</country></address><email>valery.feigin@aut.ac.nz</email><xref ref-type="aff" rid="aff3"/></contrib><contrib contrib-type="author"><name><surname>Martins</surname><given-names>Sheila C.O.</given-names></name><address><country country="BR">Brazil</country></address><email>valery.feigin@aut.ac.nz</email><xref ref-type="aff" rid="aff4"/></contrib><contrib contrib-type="author"><name><surname>Hankey</surname><given-names>Graeme J.</given-names></name><address><country country="AU">Australia</country></address><email>valery.feigin@aut.ac.nz</email><xref ref-type="aff" rid="aff5"/></contrib><contrib contrib-type="author"><name><surname>Hachinski</surname><given-names>Vladimir</given-names></name><address><country country="CA">Canada</country></address><email>valery.feigin@aut.ac.nz</email><xref ref-type="aff" rid="aff6"/></contrib></contrib-group><aff-alternatives id="aff1"><aff><institution xml:lang="en">Danube University</institution></aff><aff><institution xml:lang="ru">Дунайский университет</institution></aff></aff-alternatives><aff-alternatives id="aff2"><aff><institution xml:lang="en">Auckland University of Technology</institution></aff><aff><institution xml:lang="ru">Оклендский технологический университет</institution></aff></aff-alternatives><aff-alternatives id="aff3"><aff><institution xml:lang="en">Lund University</institution></aff><aff><institution xml:lang="ru">Лундский университет</institution></aff></aff-alternatives><aff-alternatives id="aff4"><aff><institution xml:lang="en">Hospital de Clínicas de Porto Alegre</institution></aff><aff><institution xml:lang="ru">Больница Clínicas de Porto Alegre</institution></aff></aff-alternatives><aff-alternatives id="aff5"><aff><institution xml:lang="en">The University of Western Australia</institution></aff><aff><institution xml:lang="ru">Университет Западной Австралии</institution></aff></aff-alternatives><aff-alternatives id="aff6"><aff><institution xml:lang="en">Western University</institution></aff><aff><institution xml:lang="ru">Западный университет</institution></aff></aff-alternatives><pub-date date-type="pub" iso-8601-date="2020-09-14" publication-format="electronic"><day>14</day><month>09</month><year>2020</year></pub-date><volume>14</volume><issue>3</issue><issue-title xml:lang="en"/><issue-title xml:lang="ru"/><fpage>5</fpage><lpage>10</lpage><history><date date-type="received" iso-8601-date="2020-09-14"><day>14</day><month>09</month><year>2020</year></date></history><permissions><copyright-statement xml:lang="en">Copyright ©; 2020, Brainin M., Feigin V.l., Norrving B., Martins S.C., Hankey G.J., Hachinski V.</copyright-statement><copyright-statement xml:lang="ru">Copyright ©; 2020, Brainin M., Feigin V.l., Norrving B., Martins S.C., Hankey G.J., Hachinski V.</copyright-statement><copyright-year>2020</copyright-year><copyright-holder xml:lang="en">Brainin M., Feigin V.l., Norrving B., Martins S.C., Hankey G.J., Hachinski V.</copyright-holder><copyright-holder xml:lang="ru">Brainin M., Feigin V.l., Norrving B., Martins S.C., Hankey G.J., Hachinski V.</copyright-holder><ali:free_to_read xmlns:ali="http://www.niso.org/schemas/ali/1.0/"/><license><ali:license_ref xmlns:ali="http://www.niso.org/schemas/ali/1.0/">https://creativecommons.org/licenses/by/4.0</ali:license_ref></license></permissions><self-uri xlink:href="https://annaly-nevrologii.com/pathID/article/view/677">https://annaly-nevrologii.com/pathID/article/view/677</self-uri><abstract xml:lang="en"><p>Сurrent strategies of primary stroke and cardiovascular disease prevention are aimed at addressing the main risk factors primarily in patients with higher cardiovascular disease risk. Since the number of people with incident stroke and ischaemic heart disease cases is rapidly growing across all countries of the world, this preventive strategy appears to be not sufficiently effective. World Stroke Organization recently (2020) endorsed a different concept of stroke and dementia prevention based on a population-wide approach to dealing with risk factors, which involves all individuals regardless of their cardiovascular disease risk level. This article describes four main primary prevention strategies suggested by the World Stroke Organization to effectively reduce stroke and dementia incidence by 50% and 30% respectively. These strategies include (1) population-wide prevention; (2) polypill therapy; (3) free e-Health application “Stroke Riskometer”; and active engagement of community health workers.</p></abstract><trans-abstract xml:lang="ru"><p>Современные направления первичной профилактики инсульта и сердечно-сосудистых заболеваний направлены на коррекцию основных факторов риска, прежде всего среди пациентов, относящихся к группе лиц с высоким риском сердечно-сосудистой патологии. В связи с тем что заболеваемость инсультом и ишемической болезнью сердца продолжает неуклонно расти во всех странах, данная профилактическая стратегия представляется недостаточно эффективной. В 2020 г. Всемирной организацией по борьбе с инсультом была предложена иная концепция профилактики инсульта и деменции, основанная на общепопуляционном подходе к борьбе с факторами риска, применимому ко всему населению вне зависимости от уровня сердечно-сосудистогориска. Встатье освещены четыре основные стратегии первичной профилактики,предложенные Всемирнойорганизацией по борьбе с инсультом, направленные на эффективное снижение заболеваемости инсультом и деменцией на 50% и 30% соответственно. Данные стратегии включают (1) общепопуляционную профилактику, (2) терапию полипиллами, (3) использование бесплатного мобильного приложения электронного здравоохранения «Рискометр инсульта» и (4) активное привлечение к профилактике работников общественного здравоохранения.</p></trans-abstract><kwd-group xml:lang="en"><kwd>global disease prevention</kwd><kwd>stroke</kwd><kwd>dementia</kwd><kwd>cardiovascular disease</kwd><kwd>polypill</kwd><kwd>“Stroke Riskometer”</kwd></kwd-group><kwd-group xml:lang="ru"><kwd>глобальная профилактика заболеваний</kwd><kwd>инсульт</kwd><kwd>деменция</kwd><kwd>сердечно-сосудистые заболевания</kwd><kwd>полипилл</kwd><kwd>«Рискометр инсульта»</kwd></kwd-group><funding-group/></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><mixed-citation>Hankey Graeme J. Population impact of potentially modifiable risk factors for stroke. Stroke 2020; 51: 719–728. DOI: 10.1161/STROKEAHA.119.024154. 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