Annals of Clinical and Experimental NeurologyAnnals of Clinical and Experimental NeurologyАнналы клинической и экспериментальной неврологии2075-54732409-2533Eco-Vector76110.54101/ACEN.2021.3.8TechnologiesТехнологииResearch ArticleFeatures of sodium magnetic resonance spectroscopy and its application in neurologyОсобенности методики натриевой магнитно-резонансной спектроскопии и её применение в неврологииhttps://orcid.org/0000-0003-2285-2725SinkovaViktoriya V.СиньковаВиктория Викторовна
Russian Federation

resident, Neuroradiology department

ординатор отд. лучевой диагностики

kattorina@list.ruhttps://orcid.org/0000-0001-5823-9434KrotenkovaIrina A.КротенковаИрина Андреевна
Russian Federation

Cand. Sci. (Med.), researcher, Neuroradiology department

к.м.н., н.с. отд. лучевой диагностики

kattorina@list.ruhttps://orcid.org/0000-0001-8062-0784LyaskovikAlina A.ЛясковикАлина Анатольевна
Russian Federation

resident, Neuroradiology department

ординатор отд. лучевой диагностики

kattorina@list.ruhttps://orcid.org/0000-0001-5539-245XKonovalovRodion N.КоноваловРодион Николаевич
Russian Federation

Cand. Sci. (Med.), senior researcher, Neuroradiology department

к.м.н., с.н.с. отд. лучевой диагностики

kattorina@list.ruhttps://orcid.org/0000-0003-3820-4554KrotenkovaMarina V.КротенковаМарина Викторовна
Russian Federation

D. Sci. (Med.), Head, Neuroradiology department

д.м.н., рук. отд. лучевой диагностики

kattorina@list.ruResearch Center of NeurologyФГБНУ «Научный центр неврологии»0410202115372790410202104102021Copyright ©; 2021, Sinkova V.V., Krotenkova I.A., Lyaskovik A.A., Konovalov R.N., Krotenkova M.V.Copyright ©; 2021, Синькова В.В., Кротенкова И.А., Лясковик А.А., Коновалов Р.Н., Кротенкова М.В.2021Sinkova V.V., Krotenkova I.A., Lyaskovik A.A., Konovalov R.N., Krotenkova M.V.Синькова В.В., Кротенкова И.А., Лясковик А.А., Коновалов Р.Н., Кротенкова М.В.https://creativecommons.org/licenses/by/4.0https://annaly-nevrologii.com/pathID/article/view/761

Magnetic resonance spectroscopy is an important non-invasive method that measures concentration and spatial distribution of certain biochemically significant tissue metabolites. This relatively new method has now evolved from a research tool to an independent diagnostic neuroimaging method, which provides answers to a number of important clinical and diagnostic questions at the early stages of the disease, and allows evaluation of treatment efficacy and determination of clinical outcome.

The article provides a review of data on sodium magnetic resonance spectroscopy, which is a very sensitive method for assessing cell viability and ion homeostasis. It can be used to measure early biochemical disturbances in the tissues in various degenerative diseases. We describe pathophysiology and technology underlying sodium magnetic resonance spectroscopy, as well as the most promising points of application of this method in central nervous system disorders seen by radiologists and neurologists in their clinical practice.

Магнитно-резонансная спектроскопия является важным неинвазивным методом, основанным на определении концентрации и оценке пространственного распределения конкретных биохимически значимых тканевых метаболитов. Сегодня он превратился из научно-исследовательского инструмента в самостоятельный диагностический метод нейровизуализации, позволяющий ответить на ряд важных клинико-диагностических вопросов на ранней стадии заболевания, а также оценить эффективность проводимой терапии и дать клинический прогноз.

В статье приводится обзор данных о натриевой магнитно-резонансной спектроскопии, которая является очень чувствительным методом оценки жизнеспособности клеток и ионного гомеостаза, может использоваться для измерения ранних биохимических нарушений в тканях при различных дегенеративных заболеваниях. Изложены патофизиологические основы натриевой магнитно-резонансной спектроскопии, технические основы её применения, а также основные перспективные точки приложения данного метода в контексте различных заболеваний центральной нервной системы, которые встречаются в практике рентгенологов и неврологов.

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