Эпилепсия и сон

A. G. Broutian1, A. I. Belyakova-Bodina1
1ФГБНУ «Научный центр неврологии», Москва, Россия

Аннотация


Настоящий обзор посвящен взаимосвязи между клинико-электрофизиологическими проявлениями различных форм эпилепсии и уровнем бодрствования, глубиной сна. При некоторых эпилептических синдромах приступы возникают преимущественно или исключительно во сне. Многочисленные данные свидетельствуют о том, что эпилепсия может модифицировать нормальные паттерны сна. С другой стороны, сон влияет на интериктальную эпилептиформную активность, усиливая ее, а также изменяя морфологию и распространение разрядов в зависимости от глубины сна. Если для фокальной эпилепсии характерно нарастание интериктальной активности во сне, то при генерализованных формах паттерны распределения во время сна и бодрствования более разнообразны, что отражает, вероятно, различия в патофизиологических механизмах этих эпилептических феноменов. Дальнейшие исследования могут пролить свет на механизмы формирования эпилептических нейрональных сетей, а также характер их взаимосвязи с функционированием систем, регулирующих цикл сон–бодрствование.

Литература

 


Ключевые слова

эпилепсия; сон; электроэнцефалография; эпилептические приступы; стадии сна; циклические альтернирующие паттерны

Полный текст:

PDF

Литература

Carreño M., Fernández S. Sleep-related epilepsy. Curr Treat Options Neurol 2016; 18(5): 23. DOI: 10.1007/s11940-016-0402-9. PMID: 27059342.

Janz D. The grand mal epilepsies and the sleeping-waking cycle. Epilepsia 1962; 3: 69-109. PMID: 14451274.

Binnie C.D., Stefan H. Modern electroencephalography: its role in epilepsy management. Clin Neurophysiol 1999; 110(10): 1671-1697. PMID: 10574283.

Rechtschaffen A., Kales A. (eds.) A Manual of Standardized Terminology, Techniques, and Scoring System for Sleep Stages of Human Subjects. US Department of Health, Education, and Welfare Public Health Service – NIH/NIND, 1968.

Iber C., Ancoli-Israel S., Chesson A., Quan S.F. (eds.) The AASM manual for the scoring of sleep and associated events: rules, terminology, and technical specification, 1st ed. Westchester, IL: American Academy of Sleep Medicine, 2007.

Terzano M.G., Parrino L., Garofalo P.G. et al. Activation of partial seizures with motor signs during cyclic alternating pattern in human sleep. Epilepsy Res 1991; 10(2-3): 166-173. PMID: 1817956.

Crespel A., Baldy-Moulinier M., Coubes P. The relationship between sleep and epilepsy in frontal and temporal lobe epilepsies: practical and physiopathologic considerations. Epilepsia 1998; 39(2): 150-157. PMID: 9577994.

Bazil C.W., Walczak T.S. Effects of sleep and sleep stage on epileptic and nonepileptic seizures. Epilepsia 1997; 38(1): 56-62. PMID: 9024184.

Herman S.T., Walczak T.S., Bazil C.W. Distribution of partial seizures during the sleep–wake cycle: differences by seizure onset site. Neurology 2001; 56(11): 1453-1459. DOI: 10.1212/WNL.56.11.1453. PMID: 11402100.

Minecan D., Natarajan A., Marzec M., Malow B. Relationship of epileptic seizures to sleep stage and sleep depth. Sleep 2002; 25(8): 899-904. doi:10.1093/sleep/25.8.56 PMID: 12489898

Ramgopal S., Vendrame M., Shah A. et al. Circadian patterns of generalized tonic-clonic evolutions in pediatric epilepsy patients. Seizure 2012; 21(7): 535-539. DOI: 10.1016/j.seizure.2012.05.011. PMID: 22717517.

Durazzo T.S., Spencer S.S., Duckrow R.B. et al. Temporal distributions of seizure occurrence from various epileptogenic regions. Neurology 2008; 70(15):1265-1271. DOI: 10.1212/01.wnl.0000308938.84918.3f. PMID: 18391158.

Goldenholz D.M., Rakesh K., Kapur K., et al. Different as night and day: Patterns of isolated seizures, clusters, and status epilepticus. Epilepsia 2018; 59(5): e73-e77. DOI: 10.1111/epi.14076. PMID: 29683201.

Malow A., Bowes R.J., Ross D. Relationship of temporal lobe seizures to sleep and arousal: a combined scalp-intracranial electrode study. Sleep 2000; 23(2): 231-234. PMID: 10737340.

Kostopoulos G.K. Spike-and-wave discharges of absence seizures as a transformation of sleep spindles: the continuing development of a hypothesis. Clin Neurophysiol 2000; 111 (Suppl.): S27-38. PMID: 10996552.

Ross J.J., Johnson L.C., Walter R.D. Spike and wave discharges during stages of sleep. Arch Neurol 1966; 14(4): 399-407. PMID: 4955772.

Kellaway P., Frost J.D., Crawley J.W. Time modulation of spike-and-wave activity in generalized epilepsy. Ann Neurol 1980; 8(5): 491-500. DOI: 10.1002/ana.410080506. PMID: 7192070.

Seneviratne U., Boston R.C., Cook M.J., D’Souza W.J. Characteristics of epileptiform discharge duration and interdischarge interval in genetic generalized epilepsies. Front Neurol 2018; 9. DOI: 10.3389/fneur.2018.00036. PMID:29520250.

Parrino L., Smerieri A., Spaggiari M.C., Terzano M.G. Cyclic alternating pattern (CAP) and epilepsy during sleep: How a physiological rhythm modulates a pathological event. Clin Neurophysiol 2000; 111 (Suppl. 2): 39-46. DOI:10.1016/S1388-2457(00)00400-4. PMID: 10996553.

Sato S., Dreifuss F.E., Penry J.K. The effect of sleep on spike-wave discharges in absence seizures. Neurology 1973; 23(12): 1335-1345. PMID: 4357115.

Autret A., Lucas B., Laffont F. et al. Two distinct classifications of adult epilepsies: by time of seizures and by sensitivity of the interictal paroxysmal activities to sleep and waking. Electroencephalogr Clin Neurophysiol 1987; 66(3): 211-218.PMID: 2434304.

Horita H., Uchida E., Maekawa K. Circadian rhythm of regular spikewave discharges in childhood absence epilepsy. Brain Dev 1991; 13(3): 200-202.PMID: 1928615.

Halász P., Terzano M.G., Parrino L. Spike-wave discharge and the microstructure of sleep-wake continuum in idiopathic generalised epilepsy. Neurophysiol Clin 2002; 32(1): 38-53. DOI: 10.1016/S0987-7053(01)00290-8. PMID: 11915485.

Malow B.A., Kushwaha R., Lin X. et al. Relationship of interictal epileptiform discharges to sleep depth in partial epilepsy. Electroencephalogr Clin Neurophysiol 1997; 102(1): 20-26. PMID: 9060851.

Ferrillo F., Beelke M., De Carli F. et al. Sleep-EEG modulation of interictal epileptiform discharges in adult partial epilepsy: a spectral analysis study. Clin Neurophysiol 2000; 111(5): 916-923. PMID: 10802464.

Frauscher B., Von Ellenrieder N., Ferrari-Marinho T. et al. Facilitation of epileptic activity during sleep is mediated by high amplitude slow waves. Brain 2015; 138(6): 1629-1641. DOI: 10.1093/brain/awv073. PMID: 25792528.

Billard C., Autret A., Markabi S. et al. The influence of vigilance states on paroxysmal EEG activities and clinical seizures in children. Electroencephalogr Clin Neurophysiol 1990; 75(3): 127-135. PMID: 1689635.

Sammaritano M., Gigli G.L., Gotman J. Interictal spiking during wakefulness and sleep and the localization of foci in temporal lobe epilepsy. Neurology 1991; 41(2): 290-297. PMID: 1992379.

Malow B.A., Lin X., Kushwaha R., Aldrich M.S. Interictal spiking increases with sleep depth in temporal lobe epilepsy. Epilepsia 1998; 39(12): 1309-1316. DOI: 10.1111/j.1528-1157.1998.tb01329.x. PMID: 9860066.

Clemens Z., Janszky J., Szucs A. et al. Interictal epileptic spiking during sleep and wakefulness in mesial temporal lobe epilepsy: a comparative study of scalp and foramen ovale electrodes. Epilepsia 2003; 44(2): 186-192. PMID: 12558572.

Clemens Z., Janszky J., Clemens B. et al. Factors affecting spiking related to sleep and wake states in temporal lobe epilepsy (TLE). Seizure 2005; 14(1): 52-57. DOI: 10.1016/j.seizure.2004.09.003. PMID: 15642501.

Rossi G.F., Colicchio G., Pola P. Interictal epileptic activity during sleep: a stereo-EEG study in patients with partial epilepsy. Electroencephalogr Clin Neurophysiol 1984; 58(2): 97-106. PMID: 6204846.

Malow B.A., Aldrich M.S. Localizing value of rapid eye movement sleep in temporal lobe epilepsy. Sleep Med 2000; 1(1): 57-60. PMID: 10733621.

Patry G., Lyagoubi S., Tassinari C.A. Subclinical “electrical status epilepticus” induced by sleep in children. A clinical and electroencephalographic study of six cases. Arch Neurol 1971; 24(3): 242-252. PMID: 5101616.

Peigneux P., Laureys S., Delbeuck X., Maquet P. Sleeping brain, learning brain. The role of sleep for memory systems. Neuroreport 2001; 12(18): A111-124. PMID: 11742260.

Terzano M.G., Mancia D., Salati M.R. et al. The cyclic alternating pattern as a physiologic component of normal NREM sleep. Sleep 1985; 8(2): 137-145.PMID: 4012156.

Parrino L., Ferri R., Bruni O., Terzano M.G. Cyclic alternating pattern (CAP): the marker of sleep instability. Sleep Med Rev 2012; 16(1): 27-45. DOI:10.1016/j.smrv.2011.02.003. PMID: 21616693.

Terzano M.G., Parrino L., Anelli S., Halasz P. Modulation of generalized spike-and-wave discharges during sleep by cyclic alternating pattern. Epilepsia 1989; 30(6): 772-781. PMID: 2591344.

Bonakis A., Koutroumanidis M. Epileptic discharges and phasic sleep phenomena in patients with juvenile myoclonic epilepsy. Epilepsia 2009; 50(11):2434-2445. DOI: 10.1111/j.1528-1167.2009.02110.x. PMID: 19453715.

Avanzini G., Manganotti P., Meletti S. et al. The system epilepsies: a pathophysiological hypothesis. Epilepsia 2012; 53(5): 771-778. DOI: 10.1111/j.1528-1167.2012.03462.x. PMID: 22533642.

Halász P. Are Absence Epilepsy and Nocturnal Frontal Lobe Epilepsy System Epilepsies of the Sleep/Wake System? Behav Neurol 2015; 2015: 1-15. DOI:10.1155/2015/231676. PMID: 26175547.




DOI: http://dx.doi.org/10.25692/ACEN.2018.5.14