Ultrasound neuroimaging in chronic inflammatory demyelinating polyneuropathy

Cover Page

Abstract

We present the results of ultrasound study of 21 patients with chronic inflammatory demyelinating polyneuropathy (CIDP). In 100% cases were observed changes of the ultrasound structure of peripheral nerves. The ultrasound abnormalities were most prominent in the peripheral nerves of lower extremities. The changes of both tibial and ulnar nerves morphology seem to be the most valuable for the diagnostics. The cross-sectional area of nerves does not correlate with the duration of disease that hinders the performance of the ultrasound for the purpose of follow-up.

About the authors

N. B. Vuytsik

Research Center of Neurology, Russian Academy of Medical Sciences (Moscow)

Author for correspondence.
Email: platonova@neurology.ru
Russian Federation

N. A. Suponeva

Research Center of Neurology, Russian Academy of Medical Sciences (Moscow)

Email: platonova@neurology.ru
Russian Federation

A. O. Chechetkin

Research Center of Neurology, Russian Academy of Medical Sciences (Moscow)

Email: platonova@neurology.ru
Russian Federation

M. A. Piradov

Research Center of Neurology, Russian Academy of Medical Sciences (Moscow)

Email: platonova@neurology.ru
Russian Federation

Z. A. Suslina

Research Center of Neurology, Russian Academy of Medical Sciences (Moscow)

Email: platonova@neurology.ru
Russian Federation

References

  1. Ковальчук М.О, Калинкин А.Л. Синдром беспокойных ног: патогенез, диагностика, лечение. Обзор литературы. Нервно-мышечные болезни 2013; 3: 8–19.
  2. Пирадов М.А., Супонева Н.А., Синдром Гийена-Барре: клиника, диагностика, лечение. МедПРЕСС, 2011; 200.
  3. Супонева Н.А. Клиническая и диагностическая роль аутоантител к ганглиозидам периферических нервов (обзор литературы и собственные данные). Нервно-мышечные болезни 2013; 1: 26–33.
  4. Супонева Н.А., Пирадов М.А., Никитин С.С. и др. Патогенетическая и прогностическая роль аутоантител к ганглиозидам периферических нервов при синдроме Гийена-Барре. Анналы клинич. и эксперим. неврологии 2013; 1 (7): 4–11.
  5. Супонева Н.А., Никитин С.С., Пирадов М.А., Меркулова Д.М. Хроническая воспалительная демиелинизирующая полиневропатия с острым началом и дыхательной недостаточностью. Атмосфера. Нервные болезни 2007; 1: 40–44.
  6. Duggins A.J., McLeod J.G., Pollard J.D. et al. Spinal root and plexus hypertrophy in chronic inflammatory demyelinating polyneuropathy. Brain 1999; 122: 1383–1390.
  7. Van den Bergh P.Y., Hadden R.D., Bouche P. et al. EFNS/PNS Guideline on management of chronic inflammatory demyelinating polyradiculoneuropathy: report of a joint task force of the EFNS and the PNS – First revision. Joint task force of the EFNS and the PNS. J Peripher Nerv Syst-2010; 15: 1–9.
  8. Granata G., Pazzaglia C., Calandro P. et al. Ultrasound visualization of nerve morphological alteration at the site of conduction block. Muscle Nerve 2009; 40: 1068–1070.
  9. Imamura K., Tajiri Y., Kowa H. et al: Peripheral nerve hypertrophy in chronic inflammatory demyelinating polyradiculoneuropathy detected by ultrasonography. Intern Med 2009; 48: 581–582.
  10. Matsuda M., Ikeda S., Sakurai S. et al: Hypertrophic neuritis due to chronic inflammatory demyelinating polyradiculoneuropathy (CIDP): a postmortem pathological study. Muscle Nerve 1996; 19: 163–169.
  11. Matsuoka N., Kohriyama T., Ochi K. et al: Detection of cervical nerve root hypertrophy by ultrasonography in chronic inflammatory demyelinating polyradiculoneuropathy. J Neurol Sci 2004; 219: 15–21.
  12. Mizuno K., Nagamatsu M., Hattori N. et al. Chronic inflammatory demyelinating polyradiculoneuropathy with diffuse and massive peripheral nerve hypertrophy: distinctive clinical and magnetic resonance imaging features. Muscle Nerve 1998; 805.
  13. Padua L., Hobson-Webb L.D. Ultrasound as the first choice for peripheral nerve imaging? Neurology. 2013 Apr 30; 80 (18): 1626–1627.
  14. Smith E.C., Hobson-Webb L.D., Massey E. Nerve ultrasound in motor conduction block: pre- and posttreatment findings. Muscle Nerve 2008; 38: 1369.
  15. Taniguchi N., Itoh K., Wang Y. et al. Sonographic detection of diffuse peripheral nerve hypertrophy in chronic inflammatory demyelinating polyneuropathy. J Clin Ultrasound 2000; 28: 488–491.
  16. Zaidman C.M., Al-Lozi M., Pestronk A. Peripheral nerve size in normal and patients with polyneuropathy: an ultrasound study. Muscle Nerve 2009; 40: 960–966.

Statistics

Views

Abstract: 688

PDF (Russian): 550

Article Metrics

Metrics Loading ...

Dimensions

PlumX


Copyright (c) 2017 Vuytsik N.B., Suponeva N.A., Chechetkin A.O., Piradov M.A., Suslina Z.A.

Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 International License.

This website uses cookies

You consent to our cookies if you continue to use our website.

About Cookies