Resting-state fMRI: new possibilities for studying physiology and pathology of the brain

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Abstract

A new method, resting-state fMRI, has been proposed recentl for studying basic sensory, emotional, and cognitive processes in healthy and neurologically affected subjects. It allows assessing spontaneous co-activation of different CNS regions in rest on the basis of temporal characteristics of neuronal activity of anatomically separated brain regions. On resting-state fMRI studies, the existence of stable and functionally linked restingstate brain networks was shown, that is important in the context of basic mechanisms of neurological disorders. We performed a first resting-state fMRI study in Russia in the group of 10 healthy subjects and revealed a clear default mode network pattern which was consistent with data in published papers. Examining of integrative system of functionally interacting brain regions with the use of resting-state fMRI can provide new insights into large-scale neuronal communication within the human brain.

About the authors

E. V. Seliverstova

Research Center of Neurology

Email: doctor.goody@gmail.com
Россия, Moscow

Yury A. Seliverstov

Research Center of Neurology

Author for correspondence.
Email: doctor.goody@gmail.com
ORCID iD: 0000-0002-6400-6378

Cand. Sci. (Med.), senior researcher, Scientific advisory department

Россия, Moscow

Rodion N. Konovalov

Research Center of Neurology

Email: doctor.goody@gmail.com
ORCID iD: 0000-0001-5539-245X

Cand. Sci. (Med.), senior researcher, Neuroradiology department

Россия, 125367 Moscow, Volokolamskoye shosse, 80

Sergey N. Illarioshkin

Research Center of Neurology

Email: doctor.goody@gmail.com
ORCID iD: 0000-0002-2704-6282

D. Sci. (Med.), Prof., Corr. Member of the Russian Academy of Sciences, Deputy Director, Head, Department for brain research

Россия, Moscow

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Copyright (c) 2013 Seliverstova E.V., Seliverstov Y.A., Konovalov R.N., Illarioshkin S.N.

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