Resting-state fMRI: new possibilities for studying physiology and pathology of the brain

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A new method, resting-state fMRI, has been proposed recentl for studying basic sensory, emotional, and cognitive processes in healthy and neurologically affected subjects. It allows assessing spontaneous co-activation of different CNS regions in rest on the basis of temporal characteristics of neuronal activity of anatomically separated brain regions. On resting-state fMRI studies, the existence of stable and functionally linked restingstate brain networks was shown, that is important in the context of basic mechanisms of neurological disorders. We performed a first resting-state fMRI study in Russia in the group of 10 healthy subjects and revealed a clear default mode network pattern which was consistent with data in published papers. Examining of integrative system of functionally interacting brain regions with the use of resting-state fMRI can provide new insights into large-scale neuronal communication within the human brain.

About the authors

E. V. Seliverstova

Research Center of Neurology

Russian Federation, Moscow

Yury A. Seliverstov

Research Center of Neurology

Author for correspondence.
ORCID iD: 0000-0002-6400-6378

Cand. Sci. (Med.), senior researcher, Scientific advisory department

Russian Federation, Moscow

Rodion N. Konovalov

Research Center of Neurology

ORCID iD: 0000-0001-5539-245X

Cand. Sci. (Med.), senior researcher, Neuroradiology department

Russian Federation, 125367 Moscow, Volokolamskoye shosse, 80

Sergey N. Illarioshkin

Research Center of Neurology

ORCID iD: 0000-0002-2704-6282

D. Sci. (Med.), Prof., Corr. Member of the Russian Academy of Sciences, Deputy Director, Head, Department for brain research

Russian Federation, Moscow


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Copyright (c) 2013 Seliverstova E.V., Seliverstov Y.A., Konovalov R.N., Illarioshkin S.N.

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