Clinical polymorphism of cerebrovascular disease in pathology of the brachio-cephalic arteries

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Cerebrovascular diseases are the most important cause of morbidity and mortality from cardiovascular disease among adults. Generalized atherosclerosis is the most frequent basis for vascular lesions of the brain, leading to the development of acute and chronic disorders of cerebral circulation. Polymorphism of clinical symptoms caused not only by lesions of the brachio-cephalic arteries, but also by simultaneous involvement in the variable-degree atherosclerotic rocess of other vessels, is often responsible for diagnostic difficulties. In the paper, a number of case reports describing patients with advanced atherosclerotic lesions of different vascular systems and marked variability of clinical manifestations are presented. Discussed are questions of rational diagnosis and general approaches to treatment of atherosclerosis, as well as questions of asymptomatic brachio-cephalic stenosis, “silent” brain infarcts and risk factors for atherosclerosis.


About the authors

Marine M. Tanashyan

Research Center of Neurology

Author for correspondence.
ORCID iD: 0000-0002-5883-8119

D. Sci. (Med.), Prof., Corresponding member of RAS, Deputy Director for science, Head, 1st Neurological department

Russian Federation, Moscow

Olga V. Lagoda

Research Center of Neurology

ORCID iD: 0000-0001-7562-4991

Cand. Sci. (Med.), senior researcher, 1st Neurological department, Institute of Clinical and Preventive Neurology

Russian Federation, Moscow

Alexander V. Chervyakov

Research Center of Neurology

Russian Federation, Moscow


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Copyright (c) 2012 Tanashyan M.M., Lagoda O.V., Chervyakov A.V.

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