PET-CT in early detection of Alzheimer’s disease: а case report

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Abstract

The article describes a clinical case of a female Alzheimer disease patient at an early stage of the neurodegenerative process. The patient did not have any complaints. She was taken to the neuropsychologist’s by her husband that was concerned because of the patient's family history (his mother-in-law suffered of Alzheimer's disease) and the emergence of some memory problems in his wife. The diagnosis was suspected based on the results of neuropsychological evaluation of cognitive functions which corresponded to mild cognitive impairment. To confirm the presence of a neurodegenerative disease brain positron-emission tomography with F-18 fluorodesoxyglucose (FDG) was performed. Hypometabolism of the imaging agent was detected in the temporal and parietal lobes cortex, in the association cortex of the left temporal and the right occipital lobes, and in the posterior part of the left cyngulate gyrus. This findings correlated with the data of the patient’s cognitive evaluation and thus provided the nosological diagnosis at an early stage of the disease. 

 

About the authors

Semen V. Prokopenko

Krasnoyarsk State Medical University named after Prof. V.F. Voyno-Yasenetsky

Author for correspondence.
Email: center@test.ru
Russian Federation

Boris V. Barankin

Federal Siberian Research Clinical Center

Email: center@test.ru
Russian Federation

Natal'ya М. Mar'ina

Federal Siberian Research Clinical Center

Email: center@test.ru
Russian Federation

Еlena Y. Mozheyko

Krasnoyarsk State Medical University named after Prof. V.F. Voyno-Yasenetsky

Email: center@test.ru
Russian Federation

Аnna F. Bezdenezhnykh

Krasnoyarsk State Medical University named after Prof. V.F. Voyno-Yasenetsky

Email: center@test.ru
Russian Federation

Tat'yana D. Koryagina

Krasnoyarsk State Medical University named after Prof. V.F. Voyno-Yasenetsky

Email: center@test.ru
Russian Federation

Natal'ya G. Chanchikova

Federal Siberian Research Clinical Center

Email: center@test.ru
Russian Federation

Nikolay А. Tokarev

Federal Siberian Research Clinical Center

Email: center@test.ru
Russian Federation

Еlena А. karlova

Federal Siberian Research Clinical Center

Email: center@test.ru
Russian Federation

Аnastasiya V. Ozerskaya

Federal Siberian Research Clinical Center

Email: center@test.ru
Russian Federation

Еvgeniy А. Badrin

Federal Siberian Research Clinical Center

Email: center@test.ru
Russian Federation

Кirill V. Belugin

Federal Siberian Research Clinical Center

Email: center@test.ru
Russian Federation

Аnastasiya А. Savel'eva

Federal Siberian Research Clinical Center

Email: center@test.ru
Russian Federation

Nikolay V. Shepelevich

Federal Siberian Research Clinical Center

Email: center@test.ru
Russian Federation

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Copyright (c) 2017 Prokopenko S.V., Barankin B.V., Mar'ina N.М., Mozheyko Е.Y., Bezdenezhnykh А.F., Koryagina T.D., Chanchikova N.G., Tokarev N.А., karlova Е.А., Ozerskaya А.V., Badrin Е.А., Belugin К.V., Savel'eva А.А., Shepelevich N.V.

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