Epidemiology of Huntington’s disease in the Khabarovsk Territory

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We conducted the first population-based study of Huntington’s disease (HD) in the Khabarovsk Territory (Khabarovsk, Komsomolsk-on-Amur, and 17 districts of the region). A total of 96 patients were identified, including 77 cases of familial disease (35 families), 15 cases – sporadic, and 4 – with unknown history. HD prevalence in the Khabarovsk Territory was 7.1:100 000 population. The article presents the clinical cases with rare forms of HD, confirmed by DNA diagnosis, namely Westphal juvenile form and primary akinetic-rigid adult-onset form. The role ofthorough collection of family history and molecular genetic testing to establish the correct diagnosis was emphasized.

About the authors

T. N. Proskokova

Far-Eastern State Medical University, Ministry of Health of the Russian Federation, Khabarovsk

Author for correspondence.
Email: platonova@neurology.ru
Russian Federation

A. S. Skretnev

Far-Eastern State Medical University, Ministry of Health of the Russian Federation, Khabarovsk

Email: platonova@neurology.ru
Russian Federation


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