A febrile epileptic status in a child: FIRES syndrome. A case report

Cover Page

Abstract

The article describes a clinical case of severe childhood epileptic syndrome, FIRES (DESC) syndrome, which is a form of epileptic encephalopathy in school-age children caused by hyperthermia. The emergence of this severe childhood condition leads to involvement of all diagnostic and human resources available at a pediatric critical care clinic to identify and treat this form of epileptic paroxysm. The described clinical case also had a severe course with a prolonged epileptic status, which was resistant to antiepileptic pharmacotherapy, and hyperthermia. The presented case is a modest contribution to the treasury of information about this syndrome in our country, with the aim to increase the doctors’ awareness of the problem.

About the authors

A. V. Shatalin

Vladimirsky Moscow Regional Research Clinical Institute, Moscow

Author for correspondence.
Email: platonova@neurology.ru
Russian Federation

A. S. Kotov

Vladimirsky Moscow Regional Research Clinical Institute, Moscow

Email: platonova@neurology.ru
Russian Federation

M. N. Borisova

Vladimirsky Moscow Regional Research Clinical Institute, Moscow

Email: platonova@neurology.ru
Russian Federation

M. V. Panteleeva

Vladimirsky Moscow Regional Research Clinical Institute, Moscow

Email: platonova@neurology.ru
Russian Federation

Yu. V. Matyuk

Vladimirsky Moscow Regional Research Clinical Institute, Moscow

Email: platonova@neurology.ru
Russian Federation

M. V. Romanova

Vladimirsky Moscow Regional Research Clinical Institute, Moscow

Email: platonova@neurology.ru
Russian Federation

I. Yu. Kurysheva

Vladimirsky Moscow Regional Research Clinical Institute, Moscow

Email: platonova@neurology.ru
Russian Federation

I. V. Razheva

Somatic Department № 2, Children’s Hospital, Lyubertsy District Hospital № 3, Lyubertsy, Moscow Region

Email: platonova@neurology.ru
Russian Federation

References

  1. Глебовская О.И., Березин В.Н., Понятшин А.Е. Особенности течения эпилептического статуса при FIRES-синдроме (клиническое наблюдение). Нейрохирургия и неврология детского возраста. 2012; 1 (31): 30–35.
  2. Евтушенко С.К. Разрушительные и труднокурабельные формы эпилепсии и эпилептические энцефалопатии у детей. Междунар.неврол. журн. 2012; 6 (52): 24–28.
  3. Евтушенко С.К., Омельяненко А.А. Клиническая электроэнцефалография у детей. Донецк, 2005.
  4. Левитина Е.В., Колчанова М.И., Рахманина О.А. FIRES-синдром:случай из практики. Вестник неврологии, психиатрии и нейрохирургии. 2013, 6: 80–85.
  5. Петрухин А.С., Мухин К.Ю., Холин А.А. Эпилептические энцефалопатии и схожие синдромы у детей. АртСервис Лтд., 2011.
  6. Темин П.А., Никанорова М.Ю. Эпилепсии и судорожные синдромы у детей. М.: Медицина; 1999.
  7. Эпилептология детского возраста. Руководство для врачей. Под ред. А.С. Петрухина. М.: Медицина, 2010.
  8. Mikaeloff Y., Jambague L., Hertz-Pannier et al. DESC: a pseudoencephalitis. Epilepsy Res. 2006. 69; 67–79.
  9. Nablout R. et al. Efficacy of ketogenic diet in serve refractory status epilepticus initialing fever inducted refractory epileptic encephalopathy in school age children (FIRES). Epilepsy, 2010, 10: 1528.
  10. Panayiotopoulos C.P. The educational kit on epilepsies; the epileptic syndromes. MEDICINAE 2007, vol. 2, p. 114. Available at: http://epidoc.ru/syndromes/encephalopathies/index.html.
  11. Specchio N., Fusco L., Claps D., Vigevano F. Epileptic encephalopathy in children possibly related to immune-mediated pathogenesis. Brain Dev. 2010; 32 (1): 51–56.
  12. Van Baalen A., Stephani U., Kluger G. et al. FIRES: Febrile infection responsive epileptic (FIRE) encephalopathies of school age. Brain&Development. 2009; 31: 91.
  13. Zou L.P. Fever-induced refractory epileptic encephalopathy in school-aged children: clinical features and outcome-a multicenter study on 13 children. Zhonghua Er Ke Za Zhi. 2012; 50 (8): 575–579.

Statistics

Views

Abstract: 827

PDF (Russian): 1138

Article Metrics

Metrics Loading ...

Dimensions

PlumX


Copyright (c) 2017 Shatalin A.V., Kotov A.S., Borisova M.N., Panteleeva M.V., Matyuk Y.V., Romanova M.V., Kurysheva I.Y., Razheva I.V.

Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 International License.

This website uses cookies

You consent to our cookies if you continue to use our website.

About Cookies