Intravenous thrombolysis in acute ischemic stroke

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Abstract

Strategic trend in the treatment of acute stroke resulted from thrombosis or embolization of intracerebral arteries is reperfusion of the blood flow in the ischemic area – thrombolysis. The modern methods of neuroimaging (CT and MR-angiography, diffusion and perfusion-weighted MRI, CT perfusion) play an important role in the thrombolysis decision making, as they allow to visualize the occlusion of the artery causing acute stroke, recanalization of the artery due to thrombolytic therapy, as well as the dynamics of the blood flow and metabolism in the respective brain regions. The presented clinical examples demonstrate the high efficacy of the thrombolytic treatment in acute ischemic stroke under the condition of absolute compliance with the inclusion and exclusion criteria to this therapy. The treatment of patients with acute stroke should be guided by the principles of evidence-based medicine and rely on adequate diagnostic algorithm of neuroimaging methods.

About the authors

M. A. Domashenko

Research Center of Neurology

Author for correspondence.
Email: mdomashenko@gmail.com
Россия, Moscow

Marina Yu. Maksimova

Research Center of Neurology

Email: mdomashenko@gmail.com
ORCID iD: 0000-0002-7682-6672
Россия, Moscow, Volokolamskoe shosse,80

B. А. Kistenev

Research Center of Neurology

Email: mdomashenko@gmail.com
Россия, Moscow

M. A. Loskutnikov

Research Center of Neurology

Email: mdomashenko@gmail.com
Россия, Moscow

Rodion N. Konovalov

Research Center of Neurology

Email: mdomashenko@gmail.com
ORCID iD: 0000-0001-5539-245X

Cand. Sci. (Med.), senior researcher, Neuroradiology department

Россия, 125367 Moscow, Volokolamskoye shosse, 80

V. V. Bryukhov

Research Center of Neurology

Email: mdomashenko@gmail.com
Россия, Moscow

Marina V. Krotenkova

Research Center of Neurology

Email: mdomashenko@gmail.com
ORCID iD: 0000-0003-3820-4554

D. Sci. (Med.), Head, Radiology department

Россия, 125367, Russia, Moscow, Volokolamskoye shosse, 80

Z. A. Suslina

Research Centre of Neurology

Email: mdomashenko@gmail.com
Россия, Moscow

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Copyright (c) 2008 Domashenko M.A., Maksimova M.Y., Kistenev B.А., Loskutnikov M.A., Konovalov R.N., Bryukhov V.V., Krotenkova M.V., Suslina Z.A.

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