Biomarkers of cerebral atherosclerosis: the capabilities of early diagnosis and prognosis of individual risk

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Abstract

The article discusses the results of a study of asymptomatic patients with a severe stenosing process in the brachiocephalic arteries (in a model of carotid atherosclerosis), with emphasis on determination of biochemical markers associated with various stages of atherogenesis. The definition of a group of proatherogenic and atheroprotective biomarkers is suggested and substantiated. Correlations among biomarkers are described. The correlations have potential etiopathogenetic nature, which necessitates further validation of these pathological changes in wider groups of patients.

About the authors

M. M. Tanashyan

Research Center of Neurology (Moscow)

Author for correspondence.
Email: platonova@neurology.ru
Russian Federation

A. A. Raskurazhev

Research Center of Neurology (Moscow)

Email: platonova@neurology.ru
Russian Federation

A. A. Shabalina

Research Center of Neurology (Moscow)

Email: platonova@neurology.ru
Russian Federation

O. V. Lagoda

Research Center of Neurology (Moscow)

Email: platonova@neurology.ru
Russian Federation

E. V. Gnedovskaya

Research Center of Neurology (Moscow)

Email: platonova@neurology.ru
Russian Federation

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Copyright (c) 2015 Tanashyan M.M., Raskurazhev A.A., Shabalina A.A., Lagoda O.V., Gnedovskaya E.V.

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