Neurological debut of non-Hodgkin’s lymphoma: the complexity of diagnosis

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Abstract

A rare case of system non-Hodgkin’s lymphoma manifested with oculomotor abnormalities is presented in the paper. In the patient examined, initial symptoms were diplopia and restriction of the lateral eye movements; these symptoms appeared on the background of the intense headaches. The death resulted from the acute cardio-pulmonary failure. On postmortem study, B-cell lymphoma of multiple localizations, including the central nervous system, heart, lymph nodes, spleen and liver, was found.

About the authors

R. V. Magzhanov

Bashkir State Medical University

Author for correspondence.
Email: platonova@neurology.ru
Russian Federation

K. Z. Bakhtiyarova

Bashkir State Medical University

Email: platonova@neurology.ru
Russian Federation

V. F. Tunik

G.G. Kuvatov Republican Clinical Hospital (Ufa)

Email: platonova@neurology.ru
Russian Federation

V. K. Dolganyuk

G.G. Kuvatov Republican Clinical Hospital (Ufa)

Email: platonova@neurology.ru
Russian Federation

N. A. Galliamova

G.G. Kuvatov Republican Clinical Hospital (Ufa)

Email: platonova@neurology.ru
Russian Federation

E. N. Zakirova

G.G. Kuvatov Republican Clinical Hospital (Ufa)

Email: platonova@neurology.ru
Russian Federation

E. V. Pervushina

G.G. Kuvatov Republican Clinical Hospital (Ufa)

Email: platonova@neurology.ru
Russian Federation

References

  1. Гематология: руководство для врачей (под ред. Н.Н. Мамаева, С.И. Рябова). СПб.: СпецЛит, 2008.
  2. Гончарова О.В., Липатов О.Н. Оценка распространенности неходжкинских лимфом. Мед. Вестн. Башкортостана 2009; 1: 25–28.
  3. Akaza M., Tsunemi T., Sanjo N. et al. Malignant lymphoma presented as left trigeminal neuralgia. Rinsho Shinkeigaku 2009; 49: 432–436.
  4. Arai A., Taomoto K., Yokoyama M. et al. A case of CNS metastasis from gastric MALT lymphoma. No Shinkei Geka 2009; 37: 1235–1240.
  5. Hunt K.E., Reichard K.K. Diffuse large B-cell lymphoma. Arch. Pathol. Lab. Med. 2008; 132; 118–124.
  6. Kawano N., Ochiai H., Yoshida S. et al. Clinical features and treatment outcomes of isolated secondary central nervous system lymphomas in Miyazaki Prefecture. Int. J. Clin. Oncol. 2012; 17: 336–340.
  7. Kobayashi Z., Tsuchiya K., Machida A. et al. Metastatic CNS lymphoma presenting with periventricular dissemination – MRI and neuropathological findings in an autopsy case. J. Neurol. Sci. 2009; 277:109–113.
  8. Miranda R.N., Glantz L.K., Myint M.A. et al. Stage IE non-Hodgkin’s lymphoma involving the dura: A clinicopathologic study of five cases. Arch. Pathol. Lab. Med. 1996; 120: 254–260.
  9. Muzaffar S., Siddiqui M.S., Siddiqui I. et al. Central nervous system lymphomas: a histologic and immunophenotypic analysis. J. Pak. Med.Assoc. 2000; 50: 141–144.
  10. Ono K., Arimoto H., Wada K. et al.Multicentric involvement of non-Hodgkin’s lymphoma in the central nervous system and testis-case report. Neurol. Med. Chir. 2004; 44: 493–496.
  11. Sumrall A, Herrin V. Recurrent, transformed non-Hodgkin’s lymphoma presenting as chiasmal syndrome with hyperprolactinemia and hypopituitarism. J. Miss. State Med. Assoc. 2010; 51: 35–36.

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Copyright (c) 2014 Magzhanov R.V., Bakhtiyarova K.Z., Tunik V.F., Dolganyuk V.K., Galliamova N.A., Zakirova E.N., Pervushina E.V.

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This work is licensed under a Creative Commons Attribution 4.0 International License.

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