Five-year survival after stroke

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Five-year survival of Grodno’s inhabitants who had a stroke in 2001 was investigated. Patients followed up prospectively up to 5 years from the beginning of the disease; complete data after 5 years were available for 853 of 875 patients (97.5%). The cumulative five-year death risk, 63.0%, was 2.9 times greater than for people of the same age and sex in Grodno’s general population. The relative death risk was the highest in patients younger than 45 years (55.0) and decreased to 1.1 in patients older than 84 years. The significant distinction in 5-year survival in patients with different types of stroke (subarachnoid hemorrhage – 0.68; cerebral infarction – 0.41; intracerebral hemorrhage – 0.17; undetermined stroke – 0.08) was mostly determined by the influence of acute stage rates and decreased to small non-significant values in a group of 28-day survivors. Stroke (including the recurrent episodes) was the prevalent cause of death during the first year in 28-day survivors (67.0%), where as other cardiovascular diseases were the main causes of death (62.0%) during the later period. The significant prognostic factors of the 5-year death risk after stroke were age (hazard ratio (HR) 1.04), stroke in anamnesis (HR 1.48), arterial hypertension (HR 0.76), and diabetes mellitus (1.26). In 28-day survivors the significant prognostic factors of the 5-year death risk were age (HR 1.05), stroke in anamnesis (HR 1.62), diabetes mellitus (HR 1.46), atrial fibrillation (HR 1.34), and myocardial infarction in anamnesis (HR 1.43). The obtained data shows strong necessity of secondary prevention, focused both on cerebral and heart vascular pools.


About the authors

S. D. Kulesh

Department of Neurology, Grodno State Medical University

Belarus, Grodno

S. A. Likhachev

Republican Research and Practical Center of Neurology and Neurosurgery

Belarus, Minsk

N. A. Filina

Grodno City Clinical Hospital No.1

Belarus, Grodno

A. V. Struneusky

Grodno City Clinical Hospital No.1

Belarus, Grodno

T. M. Kostinevich

Grodno Central City Outpatient Clinic

Belarus, Grodno

L. A. Kliatskova

Grodno Central City Outpatient Clinic

Belarus, Grodno

M. E. Sauchanko

Grodno Central City Outpatient Clinic

Author for correspondence.
Belarus, Grodno


  1. Вихерт А.М., Жданов В.С., Чаклин А.В. и др. Эпидемиология неинфекционных заболеваний. Под ред. А.М. Вихерта, А.В. Чаклина. М.: Медицина, 1990.
  2. Кулеш С.Д., Гордеев Я.Я., Филина Н.А. и др. Эпидемиология мозгового инсульта: результаты популяционного регистра Гродно. Сообщение I. Здравоохранение 2009; 1: 31–35.
  3. Реброва О.Ю. Статистический анализ медицинских данных. Применение пакета прикладных программ Statistica. М.: Медиа Сфера, 2006.
  4. Рябова В.С.Отдаленные последствия мозгового инсульта (по мате- риалам регистра). Журн. невропатол. и психиатр. 1986; 4 (86): 532–536.
  5. Суслина З.А., Варакин Ю.Я., Верещагин Н.В. Сосудистые заболевания головного мозга: Эпидемиология. Основы профилактики. М.: МЕДпресс-информ, 2006.
  6. Суслина З.А., Варакин Ю.Я. Клинико-эпидемиологические исследования – перспективное направление изучения церебро- васкулярной патологии (сообщение первое). Анналы клин. и эксперим. неврологии 2009; 3 (3): 4–11.
  7. Фонякин А.В., Гераскина Л.А. Роль антитромботической терапии во вторичной профилактике ишемического инсульта у пациентов с сочетанным поражением сосудистых бассейнов. РМЖ 2010; 8 (18): 451–454.
  8. Aho K., Harmsen P., Hatano S. et al. Cerebrovascular disease in the community: results of a WHO collaborative study. Bull World Health Organ 1980; 58: 113–130.
  9. Broderick J.P., Phillips S.J., O’Fallon W.M. et al. Relationship of cardiac disease to stroke occurrence, recurrence, and mortality. Stroke 1992; 23: 1250–1256.
  10. Chausson N., Olindo S., Cabre P. et al. Five-year outcome of a stroke cohort in Martinique, French West Indies: Etude Realisee en Martinique et Centree sur l’Incidence des Accidents Vasculaires Cerebraux, Part 2. Stroke 2010; 41: 594–599.
  11. Coull A.J., Rothwell P.M. Underestimation of the early risk of recurrent stroke: evidence of the need for a standard definition. Stroke 2004; 35: 1925–1929.
  12. Dennis M.S., Burn J.P.S., Sandercock P.A.G. et al. Long-term survival after first-ever stroke: the Oxfordshire Community Stroke Project. Stroke 1993; 24: 796–800.
  13. Feigin V.L., Barker-Collo S., Parag V. et al. Auckland Stroke Outcomes Study: part 1: gender, stroke types, ethnicity, and functional outcomes 5 years poststroke. Neurology 2010; 75: 1597–1607.
  14. Hankey G.J., Jamrozik K., Broadhurst R.J. et al. Five-year survival after first-ever stroke and related prognostic factors in the Perth Community Stroke Study. Stroke 2000; 31: 2080–2086.
  15. Kulesh S.D., Filina N.A., Frantava N.M. et al. Incidence and casefatality of stroke on the east border of the European Union: the Grodno Stroke Study. Stroke 2010; 41: 2726–2730.
  16. Schmidt E.V., Smirnov V.E., Ryabova V.S. Results of the seven-year prospective study of stroke patients. Stroke 1988; 19: 942–949.
  17. Woo J., Kay R., Yuen Y.K., Nicholls M.G. Factors influencing longterm survival and disability among three-month stroke survivors. Neuroepidemiology 1992; 11: 143–150.

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Copyright (c) 2012 Kulesh S.D., Likhachev S.A., Filina N.A., Struneusky A.V., Kostinevich T.M., Kliatskova L.A., Sauchanko M.E.

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