Changes in the electrical activity of the brain in patients with multiple sclerosis depending on the presence of central pain syndrome

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The electrical activity of the brain depending on the presence of central pain syndrome in patients with multiple sclerosis was analyzed. In patients with multiple sclerosis and central pain syndrome, the increase of power spectrum of electrical activity in the theta- and beta1- frequency ranges in the temporal lobes of the right hemisphere and the increase of spectral power of 2-band in the occipital, parietal and temporal lobes of both hemispheres were revealed. Data obtained and results of previous studies in patients with pathological conditions associated with nervous dys-regulation suggest that the increase in the high EEG spectrum may be a universal indicator of changes in the CNS activity in different pathologies, including the development of central pain syndrome.


About the authors

N. A. Krupina

First Moscow State Medical University named after I.M. Sechenov

Russian Federation, Moscow

M. V. Churyukanov

First Moscow State Medical University named after I.M. Sechenov

Russian Federation, Moscow

M. L. Kukushkin

Institute of General Pathology and Pathophysiology, Russian Academy of Medical Sciences

Russian Federation, Moscow

V. V. Alexeev

First Moscow State Medical University named after I.M. Sechenov

Russian Federation, Moscow

N. N. Yakhno

First Moscow State Medical University named after I.M. Sechenov

Author for correspondence.
Russian Federation, Moscow


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Copyright (c) 2011 Krupina N.A., Churyukanov M.V., Kukushkin M.L., Alexeev V.V., Yakhno N.N.

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