Electrical stimulation of the “cribriform” subthalamic nucleus in Parkinson’s disease. Clinical case and review of the literature

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Abstract

Perivascular spaces (Virchov–Robin spaces, VRS) surround the walls of vessels along their route from the subarachnoid space through the brain parenchyma. Dilated VRS are often observed by MRI in healthy people. They can be a rare cause of neurological disorders. In the literature there are a small number of cases with VRS being a probable cause of the parkinsonian syndrome or affecting the course of Parkinson’s disease (PD). We report our observation of the PD patient with complications of antiparkinsonian therapy who underwent bilateral deep brain stimulation (DBS) of the subthalamic nucleus (STN). The localization of VRS in the STN projection probably changed the clinical course of the disease but didn`t influence the outcomes of stimutation of the “cribriform” STN.

About the authors

Alexey A. Tomsky

N.N. Burdenko National Medical Research Center of Neurosurgery

Author for correspondence.
Email: atomski@nsi.ru
Russian Federation, Moscow

Anna A. Gamaleya

N.N. Burdenko National Medical Research Center of Neurosurgery

Email: atomski@nsi.ru
ORCID iD: 0000-0002-6412-8148

neurologist, Group of functional neurosurgery

Russian Federation, Moscow

Svetlana V. Asriyanz

National Medical Research Center of Neurosugrey named after N.N. Burdenko

Email: atomski@nsi.ru
Russian Federation, Moscow

Alexey S. Sedov

Semenov Institute of Chemical Physics RAS

Email: atomski@nsi.ru
Russian Federation, Moscow

Elena M. Belova

Semenov Institute of Chemical Physics RAS

Email: atomski@nsi.ru
Russian Federation, Moscow

Artem I. Batalov

National Medical Research Center of Neurosugrey named after N.N. Burdenko

Email: atomski@nsi.ru
Russian Federation, Moscow

Igor N. Pronin

National Medical Research Center of Neurosugrey named after N.N. Burdenko

Email: atomski@nsi.ru
Russian Federation, Moscow

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Copyright (c) 2018 Tomsky A.A., Gamaleya A.A., Asriyanz S.V., Sedov A.S., Belova E.M., Batalov A.I., Pronin I.N.

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