The role of micro-RNA in cerebrovascular disease

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Abstract

The article touches upon micro-RNA as new, potentially significant diagnostic, prognostic and therapeutic biomarkers in cerebrovascular pathology. Synthesis processes and effector mechanisms of micro-RNA are described. The micro-RNA that play an important role in the pathogenesis of major risk factors for cerebrovascular pathology (atherosclerosis, arterial hypertension, atrial fibrillation, diabetes mellitus) and the micro-RNA in acute cerebrovascular disorders are reviewed in detail. The need for thorough replication studies to justify the choice of micro-RNA and methods for micro-RNA detection is substantiated.

About the authors

Anton A. Raskurazhev

Research Center of Neurology

Author for correspondence.
Email: rasckey@live.com
Russian Federation, Moscow

Marine M. Tanashyan

Research Center of Neurology

Email: rasckey@live.com
Russian Federation, Moscow

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Copyright (c) 2019 Raskurazhev A.A., Tanashyan M.M.

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