Cerebral venous sinus thrombosis

Cover Page

Cite item

Full Text


The problem of cerebral venous sinus thrombosis (CVT) still stays in the focus of discussion due to the difficulties in diagnostics and treatment as a result of the small incidence and the lack of specific symptoms. Currently there are not enough publications in the field of CVT. The article discusses issues of epidemiology, clinical signs, instrumental diagnostics and the treatment of CVT.


About the authors

M. V. Glebov

Research Center of Neurology, Russian Academy of Medical Sciences

Email: glebov82@mail.ru
Russian Federation, Moscow

Marina Yu. Maximova

Research Center of Neurology

Email: glebov82@mail.ru
ORCID iD: 0000-0002-7682-6672

D. Sci (Med,), Professor, Head, 2nd Neurology department, Research Center of Neurology

Russian Federation, Moscow

M. A. Domashenko

Research Center of Neurology

Email: glebov82@mail.ru
Russian Federation, Moscow

V. V. Bryukhov

Research Center of Neurology

Author for correspondence.
Email: glebov82@mail.ru
Russian Federation, Moscow


  1. Ayanzen R.H., Bird C.R., Keller P.J. et al. Cerebral MR venography: normal anatomy and potential diagnostic pitfalls. AJNR Am. J. Neuroradiol. 2000; 21: 74–78.
  2. Bousser M.G., Ross Russel R.W. Cerebral Venous Thrombosis. London: W.B. Saunders, 1997.
  3. Canhao P., Cortesao A., Cabral M. et al. for the ISCVT Investigators: Are steroids useful for the treatment of cerebral venous thrombosis? ISCVT results. Cerebrovasc. Dis. 2004; 17 (5): 16.
  4. Cantu C., Barinagarrementeria F. Cerebral venous thrombosis associated with pregnancy and puerperium: review of 67 cases. Stroke 1993; 24: 1880–1884.
  5. De Bruijn S.F., de Haan R.J., Stam J. Clinical features and prognostic factors of cerebral venous sinus thrombosis in a prospective series of 59 patients. For The Cerebral Venous Sinus Thrombosis Study Group. J. Neurol. Neurosurg Psychiatry 2001; 70: 105–108.
  6. De Bruijn S.F., Stam J. For the Cerebral Venous Sinus Thrombosis Study Group: Randomized, placebo-controlled trial of anticoagulant treatment with low-molecular-weight heparin for cerebral sinus thrombosis. Stroke 1999; 30: 484–488.
  7. De Bruijn S.F., Stam J., Kappelle L.J. Thunderclap headache as first symptom of cerebral venous sinus thrombosis. Lancet 1996; 348: 1623–1625.
  8. Dormont D., Anxionnat R., Evrard S. et al. MRI in cerebral venous thrombosis. J. Neuroradiol. 1994; 21: 81–99.
  9. Einhäupl K., Bousser M.G., de Bruijn S.F. et al. EFNS guideline on the treatment of cerebral venous and sinus thrombosis. Eur. J. of Neurology 2006; 13: 553–559.
  10. Ferro J.M., Canhao P., Stam J. et al. Prognosis of cerebral vein and dural sinus thrombosis: results of the International Study on Cerebral Vein and Dural Sinus Thrombosis (ISCVT). Stroke 2004; 35: 664–670. 10 Том 5. № 1 2011 Контактный адрес: Глебов Максим Владимирович, канд. мед. наук, науч. сотр. 2-го неврологического отделения НЦН РАМН. Россия, 125367 Москва, Волоколамское ш., д. 80; e-mail: glebov82@mail.ru М.Ю. Максимова — докт. мед. наук, гл. науч. сотр. 2-го неврологического отделения НЦН РАМН; М.А. Домашенко — канд. мед наук, науч. сотр. 2-го неврологического отделения НЦН РАМН; В.В. Брюхов — канд. мед. наук, науч.сотр. отделения лучевой диагностики НЦН РАМН (Москва).
  11. Kuehnen J., Schwartz A., Neff W., Hennerici M. Cranial nerve syndrome in thrombosis of the transverse/sigmoid sinuses. Brain 1998; 121: 381–388.
  12. Lanska D.J., Kryscio R.J. Risk factors for peripartum and postpartum stroke and intracranial venous thrombosis. Stroke 2000; 31: 1274–1282.
  13. Manzano Palomo S., Egido Herrero J.A., Saiz A.A., Jorquera Moya M. Transient ischemic attack: the only presenting syndrome of sinus thrombosis. Neurologia 2006; 21: 155–158.
  14. Masuhr F., Busch M., Amberger N. et al. Risk and predictors of early epileptic seizures in acute cerebral venous and sinus thrombosis. Eur. J. Neurol. 2006; 13: 852–856.
  15. Masuhr F., Einhaupl K. Treatment of Cerebral Venous and Sinus Thrombosis. Handbook on cerebral venous Thrombosis. Karger, 2008.
  16. Paciaroni M., Palmerini F., Bogousslavsky J. Clinical Presentations of Cerebral Vein and Sinus Thrombosis. Handbook on cerebral venous Thrombosis. Karger, 2008.
  17. Rosendaal F.R. Venous thrombosis: a multicasual disease. Lancet 1999; 353: 1167-1173.
  18. Stam J. Thrombosis of the Cerebral Veins and Sinuses. New Eng. J. of Medicine 2005; 352: 1791–1798.
  19. Stefini R., Latronico N., Cornali C. et al. Emergent decompressive craniectomy in patients with fixed dilated pupils due to cerebral venous and dural sinus thrombosis: report of three cases. Neurosurgery 1999; 45: 626–629.
  20. Straub J., Magistry M.R., Delavelle J., Landis T. Facial palsy in cerebral venous thrombosis; Transcranial stimulation and pathophysiological considerations. Stroke 2000; 31: 1766–1769.
  21. Théaudin M., Crassard I., Bresson D. et al. Should Decompressive Surgery Be Performed in Malignant Cerebral Venous Thrombosis? A Series of 12 Patients. Stroke 2010; 41: 727–731.
  22. Vandenbroucke J.P., Rosing J., Bloemenkamp K.W. et al. Oral contraceptives and the risk of venous thrombosis. N. Engl. J. Med. 2001; 344: 1527–1535.

Supplementary files

Supplementary Files

Copyright (c) 2011 Glebov M.V., Maximova M.Y., Domashenko M.A., Bryukhov V.V.

Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 International License.

СМИ зарегистрировано Федеральной службой по надзору в сфере связи, информационных технологий и массовых коммуникаций (Роскомнадзор).
Регистрационный номер и дата принятия решения о регистрации СМИ: серия ПИ № ФС 77-83204 от 12.05.2022.

This website uses cookies

You consent to our cookies if you continue to use our website.

About Cookies