Somatosensory evoked potentials in the evaluation of motor rehabilitation efficacy in patients with ischaemic stroke

Cover Page


Cite item

Full Text

Abstract

Introduction. The quality of rehabilitation measures used during early functional recovery can be assessed by registering somatosensory evoked potentials (SSEP). In many patients, SSEP are either not recorded, or the results are poorly reproducible. To overcome these difficulties, we proposed to modify the method of recording SSEP in patients post ischaemic stroke.

The aim of the study was to evaluate changes in SSEP after patients with ischaemic stroke underwent motor rehabilitation in the early recovery period. 

Materials and methods. We examined 36 patients with acute ischaemic stroke in the middle cerebral artery territory. The severity of neurological deficits and the functional state of the nervous system were assessed using international clinical scales, based on electrophysiological and neuroimaging studies. The motor rehabilitation consisted of 10 sessions. SSEP were measured before and after the full motor rehabilitation course. We calculated the standard values for SSEP. 

Results. Before rehabilitation, SSEP were not detected in the ipsilateral hemisphere in 40% of patients. After a course of rehabilitation, SSEP were detected in the majority (83%) of patients, but the values showed significant inter-individual variation, and in such patients, SSEP cannot be used as an indicator of rehabilitation effectiveness. In the group of patients whose SSEP could be reliably recorded and the main components P and N were measurable, we found that the average component latency in the ipsilateral hemisphere was N = 48 ± 15 msec and P = 55 ± 16 msec. These values are significantly higher than in the healthy population. The amplitude parameters corresponded to the published normal values. No statistically significant changes in the latency of components N and P were observed after the course of rehabilitation.

ConclusionUsing a method for measuring SSEP with spatiotemporal separation will significantly expand the range of patients whose condition, as well as the effectiveness of the rehabilitation procedures aimed at restoring lost motor function caused by ischaemic brain damage, can be monitored over time.

About the authors

Valentina M. Alifirova

Siberian State Medical University

Email: kattorina@list.ru
Russian Federation, Tomsk

Ivan V. Tolmachev

Siberian State Medical University

Email: kattorina@list.ru
Russian Federation, Tomsk

Ekaterina S. Koroleva

Siberian State Medical University

Author for correspondence.
Email: kattorina@list.ru
Russian Federation, Tomsk

Kristina S. Kucherova

Siberian State Medical University

Email: kattorina@list.ru
Russian Federation, Tomsk

References

  1. Ermakova N.G. [Psychologocal peculiarities of patients with consequences after stroke in left and right cerebral vascular accident in the course of stationary rehabilitation]. Vestnik Sankt-Peterburgskogo Universiteta. Meditsina 2008; (3): 24–31. (In Russ.)
  2. Macdonell R.A., Donnan G.A., Bladin P.F. A comparison of somatosensory evoked and motor evoked potentials in stroke. Ann Neurol 1989; 25: 68–73. doi: 10.1002/ana.410250111. PMID: 2913930.
  3. Ueno T., Hada Y., Shimizu Y., Yamada T. Relationship between somatosensory event-related potential N140 aberrations and hemispatialagnosia in patients with stroke: a preliminary study. Int J Neurosci 2018; 128: 487–494. doi: 10.1080/00207454.2017.1398155. PMID: 29076767.
  4. Thieme H., Morkisch N., Mehrholz J. et al. Mirror therapy for improving motor function after stroke. Cochrane Database Syst Rev 2018; 7: CD008449. doi: 10.1002/14651858.CD008449.pub3. PMID: 29993119.
  5. Vedala К., Motahari S.M.A., Goryawala М. et al. Quasi-stationarity of EEG for intra operative monitoring during spinal surgeries. Scientific World Journal 2014; 2014: 468269. doi: 10.1155/2014/468269. PMID: 24695792.
  6. Chai R., Naik G.R., Nguyen T.N. et al. Driver fatigue classification with independent component by entropy rate bound minimization analysis in an EEGbased system. IEEE J Biomed Health Inform 2017; 21: 715–724. DOI: 10.1109/ JBHI.2016.2532354. PMID: 26915141.
  7. Lin C.Y., Yeh Y.C., Lai K.L. et al. High-frequency somatosensory evoked potentials of normal subjects. Acta Neurol Taiwan 2009; 18: 180–186. PMID: 19960961.

Supplementary files

Supplementary Files
Action
1. JATS XML

Copyright (c) 2020 Alifirova V.M., Tolmachev I.V., Koroleva E.S., Kucherova K.S.

Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 International License.

СМИ зарегистрировано Федеральной службой по надзору в сфере связи, информационных технологий и массовых коммуникаций (Роскомнадзор).
Регистрационный номер и дата принятия решения о регистрации СМИ: серия ПИ № ФС 77-83204 от 12.05.2022.


This website uses cookies

You consent to our cookies if you continue to use our website.

About Cookies